Results 331 to 340 of about 2,949,732 (413)

Proinflammatory bone marrow niches and neutrophil activation are associated with TIGIT expression in multiple myeloma. [PDF]

Ann Hematol
Tomarchio V, Arciprete F, Di Cecca M, Maricchiolo G, Velardi V, Tafuri M, Bianchi A, Morano V, Mecorio B, Rigacci L, Crescenzi A, Zingariello M, Annibali O.   +12 more
europepmc   +1 more source

Calhm6 Governs Macrophage Polarization Through Chp1‐Camk4‐Creb1 Axis and Ectosomal Delivery in Inflammatory Responses

Advanced Science, EarlyView.
Calhm6 drives M2 macrophage polarization via the Chp1‐Camk4‐Creb1 axis, suppressing inflammation through calcium‐dependent ectosomal delivery. Calhm6 deficiency enhances M1 responses, boosting bactericidal activity but exacerbating tissue damage. LPS/IFNγ upregulate Calhm6 via Irf1, while IL‐4/Stat6 inhibits it, balancing immune outcomes.
Yanlong Xin, Xiaofan Xiong, Yan Zhang, Siyu Zhang, Shuting Zhang, Yu Yang, Yingxue Liang, Lulu Zang, Xi Chen, Wenjuan Li, Issam Halalmeh, Rui Zhou, Zongfang Li, Haowen Liu, Jing Geng   +14 more
wiley   +1 more source

Patient's satisfaction, acceptability, and feasibility of virtual reality for pain and anxiety management during bone marrow biopsy. [PDF]

Future Sci OA
Amara Y, Frikha I, Ammar M, Zghal K, Elloumi M, Mdhaffar M, Ben Mahmoud L.   +6 more
europepmc   +1 more source

Epigenetic Targeting of Senescent Cells Prevents the Deleterious Effects of Obstructive Sleep Apnea on Growing Skeleton

Advanced Science, EarlyView.
Chronic intermittent hypoxia induces premature senescence of osteoprogenitor cells in long bone metaphysis via HIF1α‐mediated EZH2‐H3k27me3 downregulation, leading to impaired bone growth. Restoration of H3K27me3 level via UTX inhibition rescues osteogenesis and growth impairment in young mice.
Xiaonan Liu, Peilin Zhang, Zhongyi Su, Yong Feng, Zhenger Zhou, Sa Pang, Yicheng Wang, Jiacheng Hu   +7 more
wiley   +1 more source

Editorial: Bone marrow aging and its impact on immunosenescence in neurological diseases. [PDF]

Front Immunol
He J, Kerr WG, Guo X, Xu D.
europepmc   +1 more source

Single Cell and Spatial Transcriptomics Define a Proinflammatory and Profibrotic Niche After Kidney Injury

Advanced Science, EarlyView.
By integrating single‐cell RNA sequencing and spatial transcriptomics, tenascin C (TNC) is unveiled as a central organizer of the proinflammatory and profibrotic niche in kidney fibrosis. TNC promotes macrophage activation through TLR4/NF‐κB signaling, leading to renal inflammation and fibrosis.
Li Li, Jinlin Liao, Yuxi Zhang, Zifu Yao, Junxin Huang, Kejia Wu, Lu Li, Yiling Peng, Haili Zhu, Xue Hong, Xi Liu, Lili Zhou, Fan Fan Hou, Haiyan Fu, Youhua Liu   +14 more
wiley   +1 more source

Antibiotic treatment limits survival of peripheral and bone marrow B-cell populations. [PDF]

Blood Adv
Sanning LS, Walker FC, Maknojia AA, Wang L, Jin H, Kalugotla G, Lovato C, King KY, Baldridge MT.   +8 more
europepmc   +1 more source

Comparison of the bone marrow composition in samples from rib, ilium, sternum, and humerus of dogs. [PDF]

J Vet Diagn Invest
Diamantino GML, Beeler-Marfisi J, Foster RA, Sears W, Defarges A, Bienzle D.   +5 more
europepmc   +1 more source

Up-regulation of Ifi27l2a expression in bone marrow monocytes contributes to glucocorticoid-induced bone loss. [PDF]

Commun Biol
Wang Z, Huang C, Liu S, Xiao P, Lu Z, Xu Y, Tian Y.   +6 more
europepmc   +1 more source

Preliminary high-dose irradiation of the recipient and associated damage of bone marrow stromal compartment enables bone marrow stroma transplantation. [PDF]

Sci Rep
Bigildeev A, Bigildeev E, Bulygina E, Tsygankova S, Gusakova M, Illarionova O.   +5 more
europepmc   +1 more source