Results 31 to 40 of about 2,378,510 (365)

Bone marrow lipofuscin [PDF]

open access: yesJournal of Clinical Pathology, 1972
Lipofuscins are commonly present in the macrophages of the marrow. In unstained preparations they may be confused with haemosiderin, but they are readily distinguished by fluorescence microscopy.In contrast to the belief that lipofuscins are a manifestation of senility, no age dependence has been demonstrated.Exceptionally large amounts have been found
K. G. A. Clark, W. M. Davidson
openaire   +3 more sources

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Distinct bone marrow blood vessels differentially regulate hematopoiesis

open access: yesNature, 2016
Bone marrow endothelial cells (BMECs) form a network of blood vessels that regulate both leukocyte trafficking and haematopoietic stem and progenitor cell (HSPC) maintenance.
T. Itkin   +19 more
semanticscholar   +1 more source

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

Postallogeneic stem cell transplant Hodgkin lymphoma: Rare presentation of an uncommon occurrence

open access: yesClinical Case Reports, 2019
Key Clinical Message Post‐transplant lymphoproliferative disorders are rare but potentially life‐threatening complication of HSCT. Although not frequently reported but PTLD can occur as a late post‐transplant complication in HSCT recipients. A high index
Raheel iftikhar   +4 more
doaj   +1 more source

Neurology and the bone marrow [PDF]

open access: yesJournal of Neurology, Neurosurgery & Psychiatry, 1997
Human bone marrow is a fascinating and complex organ. Its major function is to produce and sustain normal haemopoiesis, and in a normal adult this entails the production of more than 1011cells/day. The marrow contains most of the multipotent haemopoietic stem cells, and provides an environment for these cells to differentiate into each of the well ...
John D. Pollard, G A R Young
openaire   +3 more sources

IL-33 promotes the egress of group 2 innate lymphoid cells from the bone marrow

open access: yesJournal of Experimental Medicine, 2018
Group 2 innate lymphoid cells (ILC2s) are effector cells within the mucosa and key participants in type 2 immune responses in the context of allergic inflammation and infection.
M. Stier   +9 more
semanticscholar   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Autoimmune Cytopenias Developing Late Post Alemtuzumab-Based Allogeneic Stem Cell Transplantation: Presentation of Short Case Series from a Transplant Center

open access: yesCell Transplantation, 2020
Stem cell transplantation remains the curative option for many patients with hematological malignancies. The long-term effects of these treatments on the patients and their immune systems have been extensively investigated, but there remains a paucity of
Rebecca Lloyd   +13 more
doaj   +1 more source

Esophageal Plasmacytoma Revealed by Persistent Hiccups: A Case Report and Literature Review

open access: yesCase Reports in Gastrointestinal Medicine, 2022
Introduction. Solitary extramedullary plasmacytoma (SEP) is a rare neoplasm that is derived from monoclonal proliferation of plasma cells in the soft tissues or organs arising outside the bone marrow.
Khaoula Khalil   +2 more
doaj   +1 more source

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