Comparative outcome analyses of subchondral <i>vs</i> intra-articular bone marrow aspirate concentrate in primary osteoarthritis knee: A double-blinded randomized controlled trial protocol. [PDF]
BACKGROUND Knee osteoarthritis (OA) imposes a substantial burden through pain, functional limitation, and progressive cartilage loss. Bone marrow aspirate concentrate (BMAC) has emerged as a promising regenerative therapy for OA due to its rich ...
Nallakumarasamy A +6 more
europepmc +2 more sources
Baghdad's first success in Bone Marrow Aspirate Concentrate procedure [PDF]
Introduction- Bone Marrow Aspirate Concentrate procedure (BMAC) is a novel regenerative technique. Aim-to show BMAC's success in relieving osteoarthritic knee sufferings in Iraqi patients.
Ahmad Mansour HAMAD +2 more
doaj +3 more sources
Equine bone marrow aspirate and bone marrow aspirate concentrate are enriched with interleukin-1 receptor antagonist protein. [PDF]
Objective To analyze the cellular, growth factor, and cytokine composition of equine sternal bone marrow aspirate (BMA) and laboratory-centrifuged BMA concentrate (BMAC). Methods This was an in vitro experimental study.
Long S +4 more
europepmc +2 more sources
Side-to-side characterisation of cellular content, soluble factors and in vitro potential on chondrocytes for bone marrow aspirate concentrate and adipose-derived stromal vascular fraction. [PDF]
Orthobiologics gained popularity for the treatment of musculoskeletal pathologies, including osteoarthritis (OA). Bone marrow aspirate concentrate (BMAC) and adipose‐derived stromal vascular fraction (SVF) were reported to reduce OA symptoms ...
Ragni E +8 more
europepmc +2 more sources
Bone Marrow Aspirate Concentrate With Hip Arthroscopy in a Heterogenous Group of Patients May Result in Improved Patient-Reported Outcomes: A Systematic Review. [PDF]
Introduction: There is little literature reporting on the efficacy of bone marrow aspirate concentrate (BMAC) in conjunction with hip arthroscopy. Purpose: We sought to systematically review the literature on BMAC use following hip arthroscopy, in ...
Lee MS +12 more
europepmc +2 more sources
Short-Term Cryopreservation Preserved the Function of MSCs from Bone Marrow Aspirate Concentrate [PDF]
Bone marrow aspirate concentrate (BMAC) is increasingly recognized as a valuable orthobiologic, offering promising outcomes in reducing inflammation, alleviating pain for patients with osteoarthritis (OA) and various musculoskeletal conditions.
Jacob Singer +9 more
doaj +2 more sources
Cell-Free Aragonite-Based Scaffold With Bone Marrow Aspirate Concentrate Augmentation for Osteochondral Defects of the Knee. [PDF]
Background: Damage to the joint surface, which affects articular cartilage and the underlying subchondral bone, is a common cause for significant knee pain and disfunction. The use of CartiHeal Agili-C, a cell-free aragonite-based implant, is an emerging
Gilat R +5 more
europepmc +2 more sources
This study aimed to identify the effectiveness and potential complications on the harvest site and knee of bone marrow aspirate concentrate (BMAC) treatment of patients with Kellgren–Lawrence (K–L) grades II–III knee osteoarthritis (OA) over a minimum ...
Ji-Hoon Baek +4 more
doaj +2 more sources
Subchondral bone marrow aspirate concentrate injection improves clinical outcomes and reduces bone marrow lesions in knee osteoarthritis: 12-month retrospective analysis [PDF]
Purpose This study had two primary aims: (1) to evaluate the clinical efficacy of fluoroscopically-guided subchondral autologous bone marrow aspirate concentrate (BMAC) injection for reducing pain and improving function in patients with knee ...
Sohaib Hasan Abdullah Ezzi +7 more
doaj +2 more sources
Randomized clinical trial comparing intra-articular injection of bone marrow aspirate clot and bone marrow aspirate concentrate in grade 3 and 4 knee osteoarthritis [PDF]
Knee osteoarthritis (KOA) is a degenerative joint condition characterized by progressive cartilage deterioration and chronic pain, leading to functional impairment. Bone marrow-derived orthobiologics, such as bone marrow aspirate clot (BMA-clot) and bone
José Fábio Lana +9 more
doaj +2 more sources

