Results 191 to 200 of about 1,337,760 (297)

Semi‐mechanistic population PK/PD model to aid clinical understanding of myelodysplastic syndromes following treatment with Venetoclax and Azacitidine

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 448-459, March 2025.
Abstract Myelodysplastic syndromes (MDS) represent a group of bone marrow disorders involving cytopenias, hypercellular bone marrow, and dysplastic hematopoietic progenitors. MDS remains a challenge to treat due to the complex interplay between disease‐induced and treatment‐related cytopenias.
Neha Thakre   +5 more
wiley   +1 more source

Detection and Inhalation Hazard Assessment of Wear Particles Arising From Abrasion of Market‐relevant Graphene Reinforced Composites

open access: yesSmall, EarlyView.
Abrasion of few‐layer graphene (FLG)–epoxy composites generated respirable particles in which FLG remained fully embedded, as confirmed by correlative HR‑TEM, Raman, and ToF‑SIMS analyses. Advanced lung cell models revealed no cytotoxic or inflammatory responses, and only high‑dose epoxy particles reduced mucociliary clearance.
Govind Gupta   +20 more
wiley   +1 more source

Microfluidic Molecular Diagnostic Chips: Functional Modules, Integration Strategies, and Emerging Applications

open access: yesSmall Methods, EarlyView.
This comprehensive review delivers an engineering‐centric analysis of microfluidic molecular diagnostic chips, breaking them down into foundational modules from fluid manipulation to bio‐sensing. Beyond chip design, it evaluates sample‐to‐answer integration strategies and commercial readiness levels.
Donghoon Koo   +7 more
wiley   +1 more source

Four‐dimensional immuno‐mechanobiomaterials: Dynamic material cues that program host response to prevent fibrosis and enable regeneration

open access: yesVIEW, EarlyView.
Dynamic immuno‐mechanobiomaterials with time‐programmed mechanical adaptation orchestrate host responses through precise mechanotransduction and immune‐stromal regulation. These adaptive biomaterials minimize mechanical mismatch, attenuate the forign dy response and fibrosis, promote angiogenesis and controlled extracellular matrix remodeling, and ...
Gobinath Vellapalayam Manoharan   +4 more
wiley   +1 more source

Revisiting the Role of Day 14 Bone Marrow Biopsy in Acute Myeloid Leukemia. [PDF]

open access: yesCancers (Basel)
Jamy O   +4 more
europepmc   +1 more source

Extramedullary Plasmacytoma of Base of Tongue: A Systematic Review

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Identifying extramedullary plasmacytoma originating from the base‐of‐tongue, in order to evaluate its prevalence, characteristics, management, and treatment within the broader spectrum of head and neck extramedullary plasmacytoma.
Ori Cohen Michael   +6 more
wiley   +1 more source

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