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Bone Marrow Transplantation for Genetic Diseases

New England Journal of Medicine, 1987
Four recent editorials in the Journal have reviewed the potential for increasing the therapeutic armamentarium for genetic disease.1 2 3 4 Bone marrow transplantation has been considered in each of...
W, Krivit, C B, Whitley
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Hepatobiliary disease after bone marrow transplant

Expert Review of Gastroenterology & Hepatology, 2023
Bone marrow transplantation (BMT) is the standard treatment for several hematologic pathologies. Post-BMT patients may develop hepatobiliary complications that impact morbidity and mortality. The differential diagnosis may include drug-induced liver injury (DILI), sepsis-associated liver injury (SALI), sinusoidal obstruction syndrome (SOS), graft ...
Maria Gabriela Fernandes Dezan   +3 more
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Bone Marrow and Metabolic Bone Disease

Seminars in Musculoskeletal Radiology
AbstractThe bone marrow represents one of the largest organs in the body, with a relevant metabolic role that continues to be investigated. Numerous studies have focused on marrow adipose tissue (MAT). Evidence indicates that the bone marrow adipocytes do not only work as storage tissue but also consist of endocrine and paracrine cells, with the ...
Maria Pilar Aparisi Gómez   +1 more
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Bone Marrow Disease

2019
The bone marrow consists of active red marrow and inactive fatty marrow which is mainly situated in the extremities. Red marrow can be replaced by various conditions. Focal disease is easy to perceive; however, diffuse disease is often hard to detect. Gadolinium application can help for quantification of contrast enhancement.
Andrea Baur-Melnyk, Tobias Geith
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Histiocytic Diseases of Bone Marrow

Hematology/Oncology Clinics of North America, 1988
The disease most likely to be associated with large numbers of bone marrow storage histiocytes is Gaucher's disease. In our community of western Pennsylvania, eastern Ohio, and West Virginia, we have encountered 30 patients with Gaucher's disease during the past 25 years.
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Bone Marrow Transplantation for Genetic Diseases

Hematology/Oncology Clinics of North America, 1990
Bone marrow transplantation is the treatment of choice for a number of genetic diseases. Recently, bone marrow transplantation has been increasingly used for erythroid disorders, such as thalassemia and sickle cell anemia. A number of inherited metabolic disorders (i.e., storage diseases, leukodystrophies, and the like) may be corrected with a marrow ...
C, Lenarsky   +3 more
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