Results 41 to 50 of about 168,975 (301)

The bone marrow aspirate and biopsy in the diagnosis of unsuspected nonhematologic malignancy: A clinical study of 19 cases

BMC Cancer, 2005
Background Although bone marrow metastases can be found commonly in some malignant tumors, diagnosing a nonhematologic malignancy from marrow is not a usual event.
Evrensel Turkkan, Kurt Ender, Ozturk Hulya, Ozan Ulku, Ozcelik Tulay, Ozkocaman Vildan, Ali Rıdvan, Ozkalemkas Fahir, Yerci Omer, Tunali Ahmet   +9 more
doaj   +1 more source

Correlation Between Bone Marrow Aspiration and Bone Marrow Biopsy with Imprint Smears in Hematological Disorders [PDF]

National Journal of Laboratory Medicine, 2016
Introduction: Bone marrow examination is an important diagnostic tool and the cornerstone of hematology. It involves the use of Bone marrow aspiration (BMA), Bone marrow imprint (BMI) and Bone marrow biopsy (BMB).
Shefali Verma , Rani Bansal, Suprabha Sharma , Abhishek Gupta, Mamta Gupta , Shiwangi Garg, Saumya Mishra   +6 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Bone marrow abnormalities in HIV infected children, report of three cases and review of the literature

Journal of Research in Medical Sciences, 2014
Bone marrow abnormalities in HIV infected adults include hypocellularity, myelodysplasia and poor marrow recovery. Data in children is limited. We report a series of three HIV infected with varied bone marrow abnormalities.
Ira Shah, Anuradha Murthy
doaj  

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Plasmodium in the bone marrow: case series from a hospital in Pakistan, 2007–2015

Malaria Journal, 2021
Background Malaria is a life-threatening, multisystem disease caused by the plasmodial parasite with a global incidence of approximately 229 million annually.
Muhammad Shariq Shaikh, Basim Ali, Mahin Janjua, Ayesha Akbar, Syed Arish Haider, Bushra Moiz, Ahmed Raheem, John Kevin Baird, Mohammad Asim Beg   +8 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Yield of Bone Marrow Examination in Diagnosis of HIV Infected Patients with Fever of Unknown Origin

Siriraj Medical Journal, 2014
Background:  HIV-infected patients are commonly found with fever of unknown origin (FUO), leading to high morbidity, prolonged hospitalization, and extensive diagnosis.
Patama Suttha
doaj  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Bone Marrow Aspirate – A Diagnostic Tool in Hematology, Importance, and Applications: Experience from Jordanian Royal Medical Services

Journal of Applied Hematology
BACKGROUND: A bone marrow aspirate is a medical procedure used to extract a small amount of bone marrow fluid and cells for examination under microscope. It is a very useful diagnostic tool in hematological field.
Mohammad J. Maaita, Abdullah Alshawabkeh, Manar AlJaafreh, Talal Mwafaq, Mohammad N. Almanaseer, Saif N. Alshoubaki, Elham A. Alsmadi   +6 more
doaj   +1 more source