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The current status of bone marrow transplantation is reviewed. The diseases that are treatable with marrow transplantation, the basic transplant procedure, and the potential complications of marrow transplantation are discussed in detail. The future application of marrow transplantation to additional disease processes is considered.
C B, Thompson, E D, Thomas
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Vaccine-induced thrombotic thrombocytopenia (VITT): first report from India
Background Vaccine-induced thrombotic thrombocytopenia (VITT) is a rare but devastating adverse event following adenoviral vector-based vaccinations for COVID-19, resulting in thrombosis, especially of the cerebral and splanchnic vasculature. Despite the
Christy V. John+5 more
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Following publication of the original article [1], the authors reported that the incorrect Fig. 2A was published in the article. The recovery times required to achieve a normal neutrophil count was omitted. The corrected Fig.
Mengqi Jin+9 more
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Evidence for engraftment of human bone marrow cells in non-lethally irradiated baboons [PDF]
Background. Prior to organ harvesting, an attempt was made to modulate the donor's immune responses against prospective xenogeneic recipients by infusion of 'recipient-type' bone marrow. Methods.
Fontes, P+7 more
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Background BCR::ABL1-like acute lymphoblastic leukaemia (BCR::ABL1-like ALL) is characterized by inferior outcomes. Current efforts concentrate on the identification of molecular targets to improve the therapy results.
Anna Płotka+10 more
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Bone marrow, or haematopoietic stem cell, transplants were originally developed to allow the use of very high dose treatments for malignancies such as leukaemia. Their use was based on the ideathat the high dose treatment might overcome inherent resistance of the malignancy to chemotherapy or radiotherapy. Transplants of stem cells from either the same
Johnson, Peter W. M., Orchard, Kim
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The Differentiation Balance of Bone Marrow Mesenchymal Stem Cells Is Crucial to Hematopoiesis. [PDF]
Bone marrow mesenchymal stem cells (BMSCs), the important component and regulator of bone marrow microenvironment, give rise to hematopoietic-supporting stromal cells and form hematopoietic niches for hematopoietic stem cells (HSCs).
Li, Shengwen Calvin+6 more
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Perioperative donor bone marrow infusion augments chimerism in heart and lung transplant recipients [PDF]
Background.: We and others have demonstrated that a low level of donor cell chimerism was present for years after transplantation in tissues and peripheral blood of heart and lung recipients; it was associated, in the latter, with a lower incidence of ...
Abdul S. Rao+34 more
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An effective treatment in Erdheim Chester disease: vemurafenib: a case report
Background Erdheim Chester disease (ECD) is a rare disease with multisystemic involvement in the group of non-langerhans cell histiocytosis. Although nearly 100 years have passed since its definition, the number of cases reported all over the world is ...
Ersin Bozan+6 more
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Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction - (TOPCARE-AMI) [PDF]
Background - Experimental studies suggest that transplantation of blood-derived or bone marrow–derived progenitor cells beneficially affects postinfarction remodeling.
Aicher, A+12 more
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