Results 181 to 190 of about 363,022 (358)

AI-driven prognostics in pediatric bone marrow transplantation: a CAD approach with Bayesian and PSO optimization. [PDF]

open access: yesBMC Med Inform Decis Mak
Badawy M   +7 more
europepmc   +1 more source

The KDM6B/SLC10A2 Axis Suppresses MDSCs Recruitment via ERK/AP‐1 Signaling in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
In wild‐type intestinal epithelial cells, KDM6B demethylates SLC10A2 to promote its expression, after which SLC10A2 suppresses ERK phosphorylation, inhibiting AP‐1 (Fos/Jun) transcription and chemokine production. In KDM6B‐deficient intestinal epithelial cells, SLC10A2 methylation increases, and its expression decreases.
Zhibo Hu   +16 more
wiley   +1 more source

A Pilot Study of Bone Marrow Transplantation in a GALT-Null Rat Model of Classic Galactosemia. [PDF]

open access: yesJIMD Rep
Rasmussen SA   +6 more
europepmc   +1 more source

Haploidentical bone marrow transplantation for AML in remission after TBF conditioning: a long-term follow-up

open access: gold
Anna Maria Raiola   +16 more
openalex   +1 more source

Targeting the Spleen as an Alternative Site for Hematopoiesis [PDF]

open access: yes, 2019
Lim, Hong   +3 more
core   +1 more source

Pre‐Existing Th1 Immunity Outperforms Age in Predicting Antibody Responses to SARS‐CoV‐2 Inactivated Vaccines

open access: yesAdvanced Science, EarlyView.
Challenging the focus on age, this study finds pre‐existing T helper 1 cells are the key biomarker for predicting antibody response to SARS‐CoV‐2 inactivated vaccines. In both mice and humans, high responders exhibited elevated baseline T helper 1 cells, which correlated with robust humoral immunity, offering crucial guidance for improving vaccine ...
Chanyuan Ye   +12 more
wiley   +1 more source

Antiemesis Corticosteroids Potentiate Checkpoint Blockade Efficacy by Normalizing the Immune Microenvironment in Metastatic Murine Breast Cancer

open access: yesAdvanced Science, EarlyView.
Corticosteroids improve the efficacy of immune checkpoint blockade therapy in metastatic murine breast cancer. By normalizing the tumor immune microenvironment, corticosteroids reduce immunosuppressive signals, restore T‐cell function, and promote antitumor immune responses, resulting in enhanced tumor control.
John D. Martin   +19 more
wiley   +1 more source

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