Results 281 to 290 of about 6,665,900 (409)

Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis.

New England Journal of Medicine, 2001
R. Neer, C. Arnaud, J. Zanchetta, R. Prince, G. Gaich, J. Reginster, A. Hodsman, E. Eriksen, S. Ish-shalom, H. Genant, O. Wang, B. Mitlak   +11 more
semanticscholar   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

High doses of methylprednisolone causes substantial muscle loss with minimal impact on bone mass and architecture in C57BL/6JRj and RjOrl:SWISS mice. [PDF]

Sci Rep
Slavensky OL, Bromer FD, Thomsen JS, Brüel A.   +3 more
europepmc   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

Unsupervised Clustering of Vertebral Hounsfield Units in Opportunistic Chest CT for Stratifying Bone Mass Subtypes in a 2 Years' Period. [PDF]

Clin Interv Aging
Yang H, Li J, Zheng X, Su D, Jia C, Qin J, Zhang Q.   +6 more
europepmc   +1 more source

RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism.

Proceedings of the National Academy of Sciences of the United States of America, 2000
Ji Li, I. Sarosi, Xiao-Qiang Yan, S. Morony, C. Capparelli, H. Tan, Susan McCabe, R. Elliott, S. Scully, Gwyneth Van, S. Kaufman, Shao Juan, Yu Sun, J. Tarpley, Laura E. Martin, Kathleen Christensen, J. Mccabe, P. Kostenuik, H. Hsu, F. Fletcher, C. Dunstan, D. Lacey, W. J. Boyle   +22 more
semanticscholar   +1 more source

Mesenchymal Stem Cell‐Derived Apoptotic Micro‐Vesicles Repaired Sciatic Nerve Defect by Regulating Early Inflammatory Microenvironment and Promoting Angiogenesis

Advanced Healthcare Materials, EarlyView.
HUCMSC‐Apo‐mvs enhance peripheral nerve repair by modulating the inflammatory microenvironment (IME), primarily through coordinated actions on three functional cells. They recruit macrophages and promote their polarization from pro‐inflammatory M1 to anti‐inflammatory M2 phenotypes, increasing secretion of IL‐10 and VEGF.
Haolin Liu, Yiben Ouyang, Bo Wang, Xiaochun Zhang, Yanjun Guan, Ruichao He, Yuhui Cui, Junli Wang, Qianru Yao, Yixiao Tan, Xiwei Peng, Xing Xiong, Sice Wang, Dongdong Li, Haofeng Cheng, Tianqi Su, Xiaoyang Fu, Jinjuan Zhao, Mingqian Yu, Yi Wang, Jiang Peng, Yu Wang   +21 more
wiley   +1 more source

In C57BL/6J mice, weight loss in previously obese mice reduced bone mass and shifted the cortical bone metabolome. [PDF]

Bone
Chlebek C, McAndrews C, Aaronson B, Welhaven HD, Yu K, Costa SN, Shaver J, Silvia S, DeMambro VE, June RK, McGee-Lawrence ME, Rosen CJ.   +11 more
europepmc   +1 more source

Giving It a Twist: One‐Step Fabrication of Aligned Biomimetic Yarn Scaffolds via Rotational Melt Electrofibrillation

Advanced Healthcare Materials, EarlyView.
Due to its multifunctionality, replicating the fibrillar and supramolecular architecture of Collagen I is gaining increasing priority in regenerative medicine. Using rotational Melt Electrofibrillation, we present a powerful method to accurately mimic the ultrastructure of Collagen with polycaprolactone, enabling the one‐step fabrication of three ...
Zan Lamberger, Vivien Priebe, Philipp Stahlhut, Kristina Andelovic, Girish Pattappa, Denitsa Docheva, Sven Heilig, Heike M. Hermanns, Taufiq Ahmad, Jürgen Groll, Gregor Lang, Matthias Ryma   +11 more
wiley   +1 more source

Risk factors of low bone mass in young patients with transfusion-dependent beta-thalassemia. [PDF]

Front Endocrinol (Lausanne)
Zhang W, Liu R, He S, Huang J, Wu L, Huang C, Liang Y, Lai Y.   +7 more
europepmc   +1 more source