Results 71 to 80 of about 6,665,900 (409)
Mir155 regulates osteogenesis and bone mass phenotype via targeting S1pr1 gene
eLife, 2023 MicroRNA-155 (miR155) is overexpressed in various inflammatory diseases and cancer, in which bone resorption and osteolysis are frequently observed. However, the role of miR155 on osteogenesis and bone mass phenotype is still unknown.
Zhichao Zheng +14 more
doaj +1 more source
p38α MAPK regulates proliferation and differentiation of osteoclast progenitors and bone remodeling in an aging-dependent manner. [PDF]
, 2017 Bone mass is determined by the balance between bone formation, carried out by mesenchymal stem cell-derived osteoblasts, and bone resorption, carried out by monocyte-derived osteoclasts.
Ao, Junping +9 more
core +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
BONE HEALTH FACTORS IN ADOLESCENTS FROM VARNA [PDF]
Journal of IMAB, 2018 Purpose: The purpose of our study is to research nutritional behavior and PA in a representative sample of 12th grade students (18-20 years of age) from Varna.
Darina N. Hristova +2 more
doaj +1 more source
Directing mesenchymal stem cells to bone to augment bone formation and increase bone mass. [PDF]
, 2012 Aging reduces the number of mesenchymal stem cells (MSCs) that can differentiate into osteoblasts in the bone marrow, which leads to impairment of osteogenesis.
Guan, Min +11 more
core +1 more source
Ultrasonic needles for bone biopsy [PDF]
, 2017 Bone biopsy is an invasive clinical procedure where a bone sample is recovered for analysis during the diagnosis of a medical condition. When the architecture of the bone tissue is required to be preserved, a core-needle biopsy is taken.
Cleary, Rebecca +5 more
core +1 more source
Nature Communications, 2016 Osteoporosis is an age-related disease that affects millions of people. Growth differentiation factor 11 (GDF11) is a secreted member of the transforming growth factor beta (TGF-β) superfamily.
Weiqing Liu +13 more
semanticscholar +1 more source
Epigenetic regulation of bone mass
Best Practice & Research Clinical Endocrinology & Metabolism, 2022 Osteoporosis, characterised by low bone mass, poor bone structure, and an increased risk of fracture, is a major public health problem. There is increasing evidence that the influence of the environment on gene expression, through epigenetic processes, contributes to variation in BMD and fracture risk across the lifecourse.
Curtis, Elizabeth +3 more
openaire +3 more sources
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
BONE DENSITOMETRY IN PATIENTS WITH RHEUMATOID ARTHRITIS [PDF]
Acta Medica Iranica, 2005 Osteoporosis (OP) is a frequent complication of rheumatoid arthritis (RA) and longitudinal studies have documented increased rate of bone loss in RA patients.
B. Heidari, F. Jalali
doaj