Results 211 to 220 of about 87,495 (307)

Injectable Chondroitin Sulfate Methacrylate Hydrogel Microspheres Co‐Loaded with GLPM Nanozyme, Dexamethasone, and Stem Cells for Synergistic Osteoarthritis Therapy

Advanced Science, EarlyView.
A multifunctional injectable microsphere system is fabricated via UV‐assisted microfluidic cross‐linking, integrating nanozyme‐based ROS scavenging, sustained dexamethasone release, and stem cell delivery. Upon IA injection, the microspheres adapt to joint stress, suppress inflammation, and promote cartilage regeneration, offering a minimally invasive ...
Xiaochen Feng, Ying Fang, Hongwei Yu, Yicheng Wang, Yunze Xu, Chunxiao Shi, Haike Xia, Ranjith Kumar Kankala, Aizheng Chen, Shibin Wang, Chaoping Fu   +10 more
wiley   +1 more source

Effect of Aging on Bone Mineral Content in Japanese Measured by Photon Absorption Wethod

, 1979
Masataka Shiraki, Hajime Orimo
openalex   +2 more sources

Rescuing Mitochondrial Dysfunction in Macrophages Prevents Osteonecrosis of the Jaw in Anti‐Resorptive Therapy

Advanced Science, EarlyView.
Schematic model showing the suggested mechanism that ZA induces classical activation of macrophages by impairing mitochondrial biofunction and inhibiting mitochondrial clearance to contribute to the pathological process of BRONJ. RAPA‐loaded nanoparticles ZDPR has shown potential in alleviating BRONJ lesions as well as treating osteoporosis or ...
Hang Zhang, Xin Shen, Haiyang Liu, Xinxi Yuan, Mumin Cao, Xuepeng Lv, Ziji Ling, Songsong Guo, Rongyao Xu, Xiang Li, Hongbing Jiang   +10 more
wiley   +1 more source

Arginine Methylation Antagonizes TEAD3‐Mediated Repression to Promote Osteogenic Differentiation by Disrupting RUNX2‐Sequestrating Condensates

Advanced Science, EarlyView.
In the unmethylated state, TEAD forms stable, repressive condensates that sequester the osteogenic master regulator RUNX2. Arginine methylation of TEAD at R55 acts as a molecular brake, dissolving these condensates to release RUNX2 and activate the osteogenic program.
Lei Cao, Ruohui Han, Hui Xiong, Qian Li, Shaofei Tao, Xudong Wu, Dayong Liu   +6 more
wiley   +1 more source

Influence of vitamin D supplementation on bone mineral content, bone turnover markers, and fracture risk in South African schoolchildren: multicenter double-blind randomized placebo-controlled trial (ViDiKids). [PDF]

J Bone Miner Res
Middelkoop K, Micklesfield LK, Walker N, Stewart J, Delport C, Jolliffe DA, Mendham AE, Coussens AK, van Graan A, Nuttall J, Tang JCY, Fraser WD, Cooper C, Harvey NC, Hooper RL, Wilkinson RJ, Bekker LG, Martineau AR.   +17 more
europepmc   +1 more source

Impact of Dehydroepiandrosterone (DHEA) on Bone Mineral Density and Bone Mineral Content in a Rat Model of Male Hypogonadism. [PDF]

Vet Sci, 2020
Sakr HF, Hussein AM, Eid EA, Boudaka A, Lashin LS.   +4 more
europepmc   +1 more source

Effects of Ovulatory and Egg Laying Cycle on Bone Mineral Density and Content of Live White Leghorns as Assessed by Dual-Energy X-Ray Absorptiometry

, 2004
M.A. Schreiweis, J. I. Orban, M. C. Ledur, D E Moody, P.Y. Hester   +4 more
openalex   +1 more source

A DNA Tetrahedron Delivery Asiatic Acid to Reprogram Mitochondrial Metabolism for Promoting Bone Regeneration via STAT3 Phosphorylation

Advanced Science, EarlyView.
A hyaluronic acid methacrylate (HAMA) hydrogel incorporating DNA tetrahedrons loaded with Asiatic acid (TDN@AA) was developed. HM‐TDN@AA promotes angiogenesis of endothelial cells (ECs), inhibits osteoclastogenesis from bone marrow–derived macrophages (BMDMs), and enhances osteogenesis of mesenchymal stem cells (MSCs) via STAT3‐mediated mitochondrial ...
Yiwen Huang, Yiming Zhang, Yisheng Feng, Qixiang Yang, Beiyuan Gao, Haiyang Xu, Cheng Huang, Kaili Lin, Yuanzhi Xu, Peiqi Zhu   +9 more
wiley   +1 more source

The Interrelationship between Arterial Calcification and Serum Estradiol Levels and Bone Mineral Content in the Aged

, 1979
Junko Nakao, Hajime Orimo, Toshiro Ooyama, Masataka Shiraki, Hideki Ito   +4 more
openalex   +2 more sources

A Biomimetic Norepinephrine‐Loaded Aligned Mineralized Collagen Scaffold for Coordinated Neurovascular, Osteogenic, and Immunomodulatory Repair of Critical‐Sized Bone Defects

Advanced Science, EarlyView.
Inspired by the composition and structure of native bone tissue and its complex interplay of biological signals, a norepinephrine‐loaded biomimetic mineralized electrocompacted collagen scaffold (NE‐MEC) is developed capable of simultaneously supporting osteogenesis, neural repair, angiogenesis, and immune modulation.
Zhengyun Ren, Zhaojun Wu, Anhang Wu, Hui Zhang, Jiachen Lu, Jiahao Zhang, Jie Weng, Jinhua Zhang, Song Chen, Huan Tan, Tailin Guo   +10 more
wiley   +1 more source