Results 301 to 310 of about 570,840 (405)

PIEZO1‐GPX4 Axis Mediates Mechanical Stress‐Induced Vertebral Growth Plate Dysplasia via Ferroptosis Activation

Advanced Science, EarlyView.
Mechanical stress activates PIEZO1 in vertebral growth plate chondrocytes, triggering ferroptosis through direct binding and inhibition of GPX4. This axis promotes lipid peroxidation and pathological ossification, accelerating spinal deformities. Clinical and genetic evidence (Piezo1‐cKO) confirms its role in scoliosis progression.
Fei Chen, Fushuai Peng, Shuqing Chen, Yukun Du, Jianyi Li, Yuanyuan Fan, Zichen Cui, Guanghui Gu, Han Zhang, Zhensong Jiang, Guodong Wang, Xingzhi Jing, Jun Dong, Tao Li, Yongming Xi   +14 more
wiley   +1 more source

Bone mineral density in IBD patients: A prospective longitudinal study

, 1998
Claudia Schulte, Axel Dignaß, Staniel Ortmans, Kenneth A. Mann, H. Goebell   +4 more
openalex   +1 more source

Bone mineral density loss in relation to the final menstrual period in a multiethnic cohort: Results from the Study of Women's Health Across the Nation (SWAN)

Journal of Bone and Mineral Research, 2012
G. Greendale, M. Sowers, Weijuan Han, Mei-hua Huang, J. Finkelstein, C. Crandall, Jennifer S. Lee, A. Karlamangla   +7 more
semanticscholar   +1 more source

Endothelial BMP6 Drives Hemodynamic‐Dependent VSMCs Calcification in Carotid Atherosclerosis

Advanced Science, EarlyView.
The study demonstrates that endothelial cell (EC)‐derived BMP6 promotes the osteogenic differentiation of vascular smooth muscle cells (VSMCs) through cell‐cell interactions. Additionally, the researchers preliminarily explore the driving effect of hemodynamic factors on BMP6‐induced calcification and reveal the regulatory role of KLF4 on BMP6.
Shen Li, Shuang Cao, Peipei Li, Feng Zhang, Gangfeng Ren, Xin Wang, Jiawei Zhao, Chen Liu, Yuan Gao, Jie Xu, Yongjun Wang, Zongping Xia, Yuming Xu   +12 more
wiley   +1 more source

Negative correlation between relative fat mass and bone mineral density: NHANES 2011-2018. [PDF]

Front Public Health
Jiang XA, Zhang HL, Ye BT, Fang SQ, Zhang JJ, Yu HL, Liang JB.   +6 more
europepmc   +1 more source

Bone Mineral Density in Precocious Puberty.

, 1996
Yuko Nakayama, Osamu Arisaka, Atsuto Hosaka, Sachi Fujiwara, Keijiro Yabuta   +4 more
openalex   +2 more sources

Ultrasound‐Mediated Biotransfection of Engineered Bone Marrow Mesenchymal Stem Cells in Treated Bone Defects through Intracellular Cavitation

Advanced Science, EarlyView.
Ultrasound‐mediated biotransfection through intracellular cavitation increases plasmid nuclear translocation and gene transfection efficiency by 284.7% and 131.6% in engineered bone marrow mesenchymal stem cells (BMSCs) compared to traditional ultrasound‐targeted microbubble destruction techniques. The maintained bone morphogenetic protein 2 expression
Zhili Xu, Huijuan Xin, Yu Wang, Renhao Xu, Yanni He, Meijun Zhou, Zhengqiang Yuan, Hongmei Liu   +7 more
wiley   +1 more source

Factors influencing bone mineral density in hyperparathyroidism phenotypes: a prospective study. [PDF]

Front Endocrinol (Lausanne)
Giocondo M, Ponte B, de Seigneux S, Sadowski SM, Bédat B, Triponez F, Demarchi MS.   +6 more
europepmc   +1 more source

CONTRIBUTIONS OF BODY COMPOSITION, ETHNICITY, AGE, AND PHYSICAL ACTIVITY TO TOTAL BODY BONE MINERAL DENSITY 964

, 1996
L. Alekel, E. Mortillaro, B. West, Rodolfo Werner, N. Ahmed, Ezekiel Hussain   +5 more
openalex   +1 more source

Targeting Multilayered Metabolic Networks in Brain Diseases: Emerging Perspectives on Nanodelivery Strategies

Advanced Science, EarlyView.
Brain diseases involve multilayered metabolic disruptions that reshape cellular interactions and microenvironments. This review outlines core metabolic features across disease states and presents emerging nanodelivery strategies as precision tools to reprogram pathological metabolism.
Jingyi Zhou, Chen Jiang
wiley   +1 more source