Results 171 to 180 of about 77,053 (361)

CDK4/6 Inhibitor Priming Enhances PD‐1 Blockade via Sellhi Neutrophil‐Induced Stat5a+ Progenitor Exhausted CD8+ T Cell

open access: yesAdvanced Science, EarlyView.
Activated tumor‐intrinsic cyclin D1‐CDK4/6 signaling attenuates lymphocyte infiltration, and consequently, and immunotherapy resistance in HNSCC. It is discovered that brief CDK4/6i priming before anti‐PD‐1 results in enhanced durability of ICB response durability through Stat5a+ progenitor exhausted CD8+ T cells induced by IL15‐secreted Sell(hi ...
Yu Zhang   +13 more
wiley   +1 more source

Closed Compression Nailing Using a New-Generation Intramedullary Nail without Autologous Bone Grafting for Humeral Shaft Nonunion [PDF]

open access: gold, 2021
Genta Fukumoto   +6 more
openalex   +1 more source

Trace Element Estimation – Methods & Clinical Context [PDF]

open access: yes, 2005
Understanding the effects of trace metals on human health is as complex as it is fascinating. As mentioned earlier, the high concentrations may prove toxic, as also, depletion in the concentration of the essential trace elements may cause various ...
Rao Nanjunda, Dr. Ananth
core   +1 more source

Virulence‐Selective Trap–Capture–Kill Antibacterial Nanostructures With Immune–Metabolic Regulation for Treating Implant‐Associated Infections

open access: yesAdvanced Science, EarlyView.
A virulence‐selective antibacterial system based on fascaplysin derivative 14‐modified TiO2 nanostructure (F‐14‐TNA) is developed for treating implant‐associated infections. F‐14‐TNA selectively traps hyperpathogenic bacteria via chemotaxis, captures them electrostatically, and kills them via reactive oxygen species‐mediated pathways.
Xiaodong Hu   +9 more
wiley   +1 more source

Nail and Bone Surface as Biomarkers for Acute Fluoride Exposure in Rats

open access: bronze, 2004
Marília Afonso Rabelo Buzalaf   +4 more
openalex   +1 more source

PDZK1 Protects Against RPE Senescence by Targeting the 14‐3‐3ε‐mTOR Axis to Attenuate Early Diabetic Retinopathy

open access: yesAdvanced Science, EarlyView.
PDZK1 down‐regulation couples high‐glucose stress to RPE senescence via a PDZK1–14‐3‐3ε–mTOR axis. Restoring PDZK1 or clearing senescent cells rescues retinal homeostasis and mitigates early diabetic retinopathy (DR). This study provides direct evidence linking RPE cell senescence to DR pathogenesis and reveals a promising therapeutic strategy for DR ...
Jian Zhao   +6 more
wiley   +1 more source

The Debt and Other Poems [PDF]

open access: yes, 2016
A selection of poems, translations, and imitations written from 2009 ...
Corbett, Kevin
core   +2 more sources

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