Predictors of complications after intramedullary nailing for lower extremity fractures in low-resource settings: a 10-year experience with the SIGN nail in Nigeria. [PDF]
Adesina SA +10 more
europepmc +1 more source
Move beyond free radical theory of aging
Free radicals play a dual, dose‐dependent role in aging. Low levels activate the key sensor adenosine 5'‐monophosphate‐activated protein kinase (AMPK), promoting cell survival mechanisms like autophagy and enhancing mitochondrial health. High levels, however, push AMPK to initiate cell death pathways, such as apoptosis. This positions AMPK as a central
Xiaofeng Dai, Meilan Hu, Ruohan Lyu
wiley +1 more source
Predictors for the necessity of open reduction in the treatment of pediatric both bone forearm fractures with elastic stable intramedullary nailing. [PDF]
Kralj R +4 more
europepmc +1 more source
Microbiome‐urothelium crosstalk in bladder cancer: From dysbiosis to clinical translation
This review elucidates the critical crosstalk between the urobiome and bladder cancer (BCa), mapping the landscape from ecological dysbiosis to clinical translation. We synthesize emerging evidence on microbial signatures that distinguish BCa patients, exploring key carcinogenic mechanisms including chronic inflammation, genotoxicity, and the gut ...
Haoxiang Xu +14 more
wiley +1 more source
Microbial metabolites in tumor epigenetic regulation
The gut microbiome modulates tumor epigenetic regulation through bioactive metabolites derived from dietary substrates. Microbiota‐produced SCFAs, secondary BAs, one‐carbon metabolites, and tryptophan‐derived ligands regulate histone acetylation, DNA methylation, and chromatin remodeling via HDAC, DNMT, AhR, and metabolic cofactor‐dependent pathways ...
Wangzheqi Zhang +31 more
wiley +1 more source
Short Versus Long Nails in Treating Subtrochanteric Hip Fractures: A Systematic Review and Meta-analysis of Complication Rates. [PDF]
Selim A, Ponugoti N, Menon D, Thomas G.
europepmc +1 more source
Tips and Tricks for Installation of the SLIM Nail in Osteogenesis Imperfecta with Narrow Medullary Canals: A Surgical Guide with Case Insights. [PDF]
Mounsef PJ, Legler J, Hamdy R.
europepmc +1 more source

