Results 71 to 80 of about 250,372 (314)

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

Advanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo, Sara Menegazzo, Marcella Pantile, Silvia Bresolin, Carlo Zanon, Alessandro Davini, Massimiliano Mazzone, Alessandra Biffi, Sanja Aveic   +8 more
wiley   +1 more source

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source

Comparison of strengths of five internal fixation methods used after bilateral sagittal split ramus osteotomy: An in vitro study

Dental Research Journal, 2020
Background: Results on the strength and displacement of internal fixation methods for bilateral sagittal split ramus osteotomy are controversial, and some designs have not been adequately studied. Therefore, this study was conducted to compare techniques
Farzin Sarkarat, Atiye Ahmady, Farzam Farahmand, Ali Fateh, Roozbeh Kahali, Amir Nourani, Vahid Rakhshan   +6 more
doaj   +1 more source

Loss of Stat3 in Prx1+ Progenitors Impairs Molar Root Development

Advanced Biology, EarlyView.
Stat3 critically regulates mandibular first molar and alveolar bone morphogenesis. Conditional ablation of Stat3 disrupts the osteogenic capacity of Prx1+ mesenchymal progenitors, as evidenced across in vivo and in vitro models. Abstract Signal Transducer and Activator of Transcription 3 (Stat3) acts as a central transcriptional modulator coordinating ...
Xin Feng, Wangyu Luo, Yichen Yao, Lichieh Lin, Laiting Chan, Jiarui Lu, Zijing Huang, Jingyi Feng, Le Zhao, Xiaolei Zhang, Liu Yang   +10 more
wiley   +1 more source

Are Anterior Plates More Effective than Iliosacral Screws to Fix the Sacroiliac Joint? Biomechanical Study [PDF]

Revista Brasileira de Ortopedia
Introduction Sacroiliac joint dislocations are caused by high energy trauma and commonly treated with the iliosacral screw fixation or the anterior plating of the sacroiliac joint (SIJ).
Flavio Goldsztajn, Jose Ricardo L. Mariolani, William Dias Belangero   +2 more
doaj   +4 more sources

Graphene–Catechol Dental Sealant: Antibacterial and Mechanical Evaluation

Advanced Engineering Materials, EarlyView.
This study presents dental sealants made with graphene and L‐DOPA‐modified graphene. L‐DOPA enhances graphene dispersion, improving sealant properties. The material shows antibacterial activity against S. mutans and L. casei, along with high strength and elasticity.
Renata Pereira, Flávio H. B. Aguiar, Rodrigo B. E. Lins, Maria C. A. J. Mainairdi, Bruna G. Silva, Marcela A. Ferretti, Klaus Rischka   +6 more
wiley   +1 more source

Comparative Study of Function and Quality of Life in Patients with Fracture of the Tibial Plateau Operated with Locked or Conventional Plates

Revista Brasileira de Ortopedia, 2019
Objective To compare clinical, functional, and quality of life outcomes between patients with tibial plateau fractures operated with locked or conventional plates, and to compare the costs of these implants.
Bruno Gonçalves Schröder e Souza, Thiago Avelino Leite, Tarsis Aparecido Bueno da Silva, Carlos Otavio Fabiano de Faria Candido, Felipe Freesz de Almeida, Valdeci Manoel de Oliveira   +5 more
doaj   +1 more source

Residual Stress States in Microstructurally Graded PBF–LB/M Austenitic Steel Components

Advanced Engineering Materials, EarlyView.
This study examines microstructurally graded 316L rectangular tube profiles fabricated via PBF–LB/M using a dual‐laser system. A 1 kW top‐hat and a 400 W Gaussian laser create distinct grain sizes and crystallographic texture. Mechanical properties are linked to microstructural evolution driven by processing conditions.
Nico Möller, Florian Loebich, Thomas Wegener, Julia Richter, Jens Gibmeier, Thomas Niendorf   +5 more
wiley   +1 more source

New Developments in the Field of Production and Application of Multi‐Material Wire Arc Additive Manufacturing Components: A Review

Advanced Engineering Materials, EarlyView.
The utilization of direct energy deposition (DED)‐arc additive manufacturing processes in industrial applications is increasing, and these processes have the potential for multi‐material applications. This work provides a overview of the state of research in DED‐arc made functional graded structures, to establish a link to potential industrial ...
Kai Treutler, Volker Wesling
wiley   +1 more source

The Effect of Thickness, Build Orientation, and Loading Rate on the Tensile and Compressive Properties of Selective Laser Sintering Polyamide 12 Specimens

Advanced Engineering Materials, EarlyView.
This article examines how build orientation, thickness, and loading rate affect the tensile and compressive properties of LS‐manufactured polyamide 12 12 parts. Through over 120 experiments, it reveals strong ductility anisotropy in tension, minimal compressive sensitivity, and significant thickness and strain rate dependencies.
Andreas Psarros, Grigorios Paraskevopoulos, Georgios Savaidis   +2 more
wiley   +1 more source