Results 101 to 110 of about 1,942,127 (402)

Biomechanical analysis of a cranial Patient Specific Implant on the interface with the bone using the Finite Element Method

, 2017
- New advance technologies based on reverse engineering , design and additive manufacturing, have expanded design capabilities for biomedical applications to include Patient Specific Implants (PSI). This change in design paradigms needs advanced tools to
Díaz, J., González-Estrada, Octavio Andrés, López, C.   +2 more
core   +1 more source

Primary stability of cementless threaded acetabular cups at first implantation and in the case of revision regarding micromotions as indicators [PDF]

, 2012
The primary stability of cementless total hip endoprosthesis is of vital importance for proximate, long-term osteointegration. The extent of micromotions between implant and acetabulum is an indicator of primary stability.
Buerkner, Andreas, Fottner, Andreas, Jansson, Volkmar, Lichtinger, Thomas, Schulze Pellengahr, Christoph von, Teske, Wolfram, Vogel, Tobias   +6 more
core   +1 more source

Dynamic Torque Limitation vs Static Torque Limitation for Bone Screws in Pig Bone

Current Directions in Biomedical Engineering
Correctly torquing bone screws is important to achieve good patient outcomes. An automated system has been previously proposed that may allow more objective torquing of bone screws. Here the system is tested vs. a static torque limit in pig bone.
Wilkie Jack, Richard Jordan, Joshi Aditya, McFarlane Zoe, Staiger Mark, Rauter Georg, Möller Knut   +6 more
doaj   +1 more source

Immersion in Raloxifene does not significantly improve bone toughness or screw pull-out strength in multiple in vitro models [PDF]

, 2021
Michael R. Eby, Danielle M. Cristino, Matthew Counihan, Kendall M. Masada, Jaimo Ahn, Michael W. Hast   +5 more
openalex   +1 more source

Modulating Integrin and Growth Factor Signaling With Peptides: Strategies to Synergistically Enhance Bone Tissue Regeneration

Advanced Science, EarlyView.
It has been demonstrated that, in the bone extracellular matrix (ECM), integrins and growth factor receptors (GFRs) engage in synergistic signaling to guide bone healing and regeneration. This review provides a comprehensive overview of current strategies using ECM‐derived peptides to recreate the cellular microenvironment and harness synergistic ...
Lluís Oliver‐Cervelló, Elisabetta Ada Cavalcanti‐Adam, Carlos Mas‐Moruno   +2 more
wiley   +1 more source

Magnesium Structure‐Function Integration Platform for Spatiotemporal Multi‐Modality Therapy: Combining Hormonotherapy and Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
The schematic illustration of the MHSCG platform for spatiotemporal responsive GRb1 release to induce androgen deprivation therapy (ADT) and immunogenic cell death (ICD) multimodal therapy in prostate cancer. Abstract Metal‐based immunotherapy represents a promising strategy for enhancing antitumor efficacy; however, its clinical application is limited
Rui Zan, Qianping Mao, Keyi Wang, Guodong Zou, Shi Yang, Hua Qiu, Xiang Fang, Guiqing Wang, Xinyi Zhou, Jiexia Wen, Shuai Jiang, Ran Huang, Qiuming Peng, Tao Suo   +13 more
wiley   +1 more source

In Situ X‐Ray Tomography and Acoustic Emission Monitoring of Damage Evolution in C/C‐SiC Composites Fabricated by Liquid Silicon Infiltration

Advanced Science, EarlyView.
This study investigates how the internal structure of fiber‐reinforced ceramic composites affects their resistance to damage. By combining 3D X‐ray imaging with acoustic emission monitoring during mechanical testing, it reveals how silicon distribution influences crack formation.
Yang Chen, Renato S. M. Almeida, Stefan Flauder, Guillaume Couégnat, Kamen Tushtev, Jürgen Horvath, Peter Wriggers, Kurosch Rezwan   +7 more
wiley   +1 more source

Osseointegration of Self-Drilling Titanium Screws in the Hole Smaller than the Screw Core in the Male Rabbit

Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Veterinary Medicine
Inserting orthopedic screws into a hole that is too small can produce excessive mechanical forces that cause osteocyte death and difficulty carrying out bone repair processes. The aim of the study was to evaluate the osseointegration of titanium screws 6
Vasile DUMA, Nicușor-Valentin OROS, Adrian Florin GAL, Maria-Cătălina MATEI-LAȚIU, Cristian Adrian RAȚIU, Vasile RUS, Cristian Olimpiu MARTONOS, Bogdan Cătălin ALEXANDRU, Liviu Ioan OANA   +8 more
doaj   +1 more source

Risk Factor Analysis of Bone Cement Leakage for Polymethylmethacrylate-Augmented Cannulated Pedicle Screw Fixation in Spinal Degenerative Diseases [PDF]

, 2021
Yaoyao Liu, Jun Xiao, Lei He, Xiang Yin, Lei Song, Rui Zhou, Jing Zeng, Peng Liu, Fei Dai   +8 more
openalex   +1 more source

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao, Jun Wang, Hanwenchen Wang, Xiang Sun, Fang Fang, Shiying Li, Jianping Liu, Changrong Shi, Pengyuan Qi, Jianhua Zou, Xiaoyuan Chen, Kailin Cai   +11 more
wiley   +1 more source