Results 211 to 220 of about 1,900,237 (384)

Targeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Chromosomal rearrangements involving the Mixed Lineage Leukemia gene (MLL1, KMT2A) are defining a genetically distinct subset in about 10% of human acute leukemias. Translocations involving the KMT2A‐locus at chromosome 11q23 are resulting in the formation of a chimeric oncogene, where the N‐terminal part of KMT2A is fused to a variety of ...
Florian Perner   +3 more
wiley   +1 more source

Negative impact of corticosteroid use on outcome in patients with advanced BTCs treated with cisplatin, gemcitabine, and durvalumab: A large real‐life worldwide population

open access: yesInternational Journal of Cancer, EarlyView.
What's new? In recent years, the possible prognostic impact of concomitant medications in patients with cancer treated with immunotherapy combinations has generated increasing interest. This real‐world analysis evaluated the impact of concomitant medications on survival outcomes in patients with advanced biliary tract cancer treated with cisplatin ...
Federica Lo Prinzi   +71 more
wiley   +1 more source

Posterior arm delivery versus the shoulder shrug maneuver in shoulder dystocia management: A simulation‐based comparative study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To compare posterior arm delivery and the shoulder shrug maneuver in shoulder dystocia. Methods A prospective, randomized, simulation‐based experimental study was conducted with six physicians managing 96 simulated shoulder dystocia cases.
Marcos Javier Cuerva   +8 more
wiley   +1 more source

A novel in silico method to quantify primary stability of screws in trabecular bone

open access: yesJournal of Orthopaedic Research, 2017
J. A. Steiner   +4 more
semanticscholar   +1 more source

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