Results 191 to 200 of about 1,508,326 (290)

Integrated Clinical and Proteomic Profiling of CD19 Chimeric Antigen Receptor T Cell Therapy in Progressive Systemic Sclerosis

open access: yesArthritis &Rheumatology, EarlyView.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia   +16 more
wiley   +1 more source

Dnmt3a Mutations Limit Normal and Autoreactive CD4+ T Follicular Helper Responses and Attenuate T Cell–Driven Joint Inflammation

open access: yesArthritis &Rheumatology, EarlyView.
Objective Somatic DNMT3A mutations are the most common drivers of clonal hematopoiesis in patients with rheumatoid arthritis (RA) and have been associated with seropositive disease and increased markers of inflammation. These mutations are predominantly hypomorphic or dominant‐negative, reducing DNMT3A function.
Yunbing Shen   +10 more
wiley   +1 more source

Risk of Cancer According to Duration of Targeted Therapy Exposure in Spondyloarthritis: A Nationwide Cohort Study From the French Health Insurance Database

open access: yesArthritis &Rheumatology, EarlyView.
Objective To assess the association between duration of targeted therapy exposure and cancer risk in patients with spondyloarthritis (SpA), including those with psoriatic arthritis, axial SpA, and other subtypes. Methods This nationwide cohort study used the French health insurance database to identify adults with SpA initiating a targeted therapy ...
Karine Tankovic   +7 more
wiley   +1 more source

Preoperative Computed Tomography Aortic Calcification and Attenuation of the Vertebral Body Predict Fractures Post-Kidney Transplantation Using Machine Learning. [PDF]

open access: yesClin Transplant
Tomizawa M   +12 more
europepmc   +1 more source

Dual‐Scaffold Technique: Autologous Minced Cartilage and Bone Marrow Aspirate Scaffold Combined With Synthetic Collagen Membrane for Cartilage Repair

open access: yesArthroscopy Techniques, EarlyView.
Abstract Treating cartilage injuries has long been a complex challenge; however, recent progress has greatly increased the variety of effective therapeutic approaches. The minced autologous matrix‐induced chondrogenesis plus procedure for full‐thickness knee cartilage lesions uses a collagen matrix combined with shaver‐minced cartilage graft and bone ...
Leonardo Ataíde   +5 more
wiley   +1 more source

Medial Meniscus Allograft Transplant: Arthroscopic Soft Tissue Technique With Suture Tape Augmentation

open access: yesArthroscopy Techniques, EarlyView.
Abstract Meniscal allograft transplant (MAT) is gaining popularity for treating meniscus deficiency. Various MAT techniques are described. Bony techniques such as bone plugs and bone slot techniques are considerably more technically challenging but show better reduction of extrusion than all‐soft‐tissue technique.
Sara N. Kiani   +3 more
wiley   +1 more source

Mesenchymal stem cells derived from gingiva normoxic or hypoxic-preconditioning allogenous transplantation affect orthodontic tooth movement in vivo. [PDF]

open access: yesJ Dent Sci
Nugraha AP   +15 more
europepmc   +1 more source

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