Results 281 to 290 of about 479,728 (360)

Targeting DAP5 Disrupts Alternate Mode of Translational Initiation in Tregs and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
Regulatory T cells (Tregs) suppress antitumor immunity. This study identifies that the translation scaffold DAP5/eIF4G2 is upregulated in tumor‐infiltrating Tregs (ti‐Tregs). DAP5 mediates an alternate translation mode to sustain CD25 and MCL‐1 expression, which is critical for ti‐Treg stability and survival in the tumor microenvironment.
Xiaojiang Lai, Guihong Pan, Xixi Feng, Jun Zhang, Yunxia Li, Shanmeizi Zhao, Zhenming Lin, Yun Feng, Wei Bao, Hongyan Yang, Chengmei Xie, Chen Huang, Jun Wang   +12 more
wiley   +1 more source

Therapeutic application of EUS-guided intraportal autologous bone marrow transplantation for decompensated liver cirrhosis. [PDF]

Stem Cell Res Ther
Cai T, Chen B, Li XM, Deng A, Shen YC, Yang XE, Liu Y, Liang LX, Liu XM, Wang F.   +9 more
europepmc   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Acute Lymphoblastic Leukemia Characterized by Rare BCR::FGFR1 Translocation: A Case Report With Literature Review

Case Reports in Hematology
Maximilian Al-Bazaz, Anika Forstreuter, Ibrahim Hammada, Jurek Hille, Jan Nicolai Wagner, Jochim Reinert, Janine Wehrhahn, Carsten Bokemeyer, Walter Fiedler   +8 more
doaj   +1 more source

Avapritinib in the treatment of systemic mastocytosis with associated acute myeloid leukemia after poor graft function following allogeneic hematopoietic stem cell transplantation: a case study and review of the literature. [PDF]

Front Oncol
Mi R, Li X, Chen L, Wang L, Ma Y, Fu Y, Wei X.   +6 more
europepmc   +1 more source

Liver transplantation: From the laboratory to the clinic and beyond [PDF]

, 1998
Marino, IR, Starzl, TE
core  

Haploidentical bone marrow transplantation for AML in remission after TBF conditioning: a long-term follow-up

Anna Maria Raiola, Carmen Di Grazia, Alida Dominietto, Stefania Bregante, Sabrina Giammarco, Riccardo Varaldo, Federica Sorà, Elisabetta Metafuni, Maria Assunta Limongiello, Antonella Laudisi, Monica Passannante, Eugenio Galli, Massimiliano Gambella, Simona Sica, Andrea Bacigalupo, Emanuele Angelucci, Patrizia Chiusolo   +16 more
openalex   +1 more source

Photoacoustic Microscopy for Multiscale Biological System Visualization and Clinical Translation

Advanced Science, EarlyView.
Photoacoustic microscopy (PAM) is a powerful biomedical imaging tool renowned for its non‐invasiveness and high resolution. This review synthesizes recent technological advances and highlights their broad applications from cellular and organ‐level to whole‐animal imaging.
Tingting Wang, Jiali Chen, Liming Nie, Honghui Li   +3 more
wiley   +1 more source

Pazopanib as maintenance therapy in pediatric ewing sarcoma: a case series of six patients. [PDF]

Mol Cell Pediatr
Bayram N, Elli M, Yaman Y, Al IO, Ozdilli K, Unal D, Ozger H, Anak S.   +7 more
europepmc   +1 more source

Autologous Bone Marrow Transplantation.

Internal Medicine, 1996
openaire   +3 more sources