Results 81 to 90 of about 283,613 (309)

Allogeneic bone marrow transplantation for infants with acute leukemia or myelodysplastic syndrome

, 2001
The objective of this study is to investigate the outcome of children 24 months or age or younger (infants) at the time of allogeneic bone marrow transplantation (BMT) for acute leukemia or myelodysplasia.
Cunningham, J. M., Pitts, N., Leung, W., Woodard, P., Bowman, L. C., Benaim, E., Horwitz, E. M., Burnette, K., Pui, C. H., Hale, G.   +9 more
core   +1 more source

Impact of Bone Marrow Aspirate Tregs on the Response Rate of Younger Newly Diagnosed Acute Myeloid Leukemia Patients

Journal of Immunology Research, 2018
Acute myeloid leukemia (AML) is widely considered a distinct clinical entity with a well-defined molecular and genetics-based prognosis. Particularly in a younger patient, the therapeutic approach depends largely on diagnostic risk stratification, which ...
Mario Delia, Paola Carluccio, Anna Mestice, Claudia Brunetti, Francesco Albano, Giorgina Specchia   +5 more
doaj   +1 more source

Coaxially Electrospun Myocardial dECM‐ Based Nanofibrous Scaffolds Demonstrate Enhanced Cardiomyocyte Biocompatibility

Advanced Healthcare Materials, EarlyView.
Our coaxial electrospinning system is capable of incorporating decellularized myocardial extracellular matrix in a core‐sheath configuration, creating nanofibrous scaffolds. These scaffolds, in turn, support the maintenance of functional cardiomyocytes adhered to the surface of these bioactive scaffolds.
Dhanusha N. Rajapakse, Mahtab Khodadadi, Kiran M. Ali, Suh Hee Cook, Bryson T. Proctor, Tanya Upadhyay, Daxian Zha, Fatema Tuj Jahura, Marziyeh Boosaliki, Jessica M. Gluck   +9 more
wiley   +1 more source

P887: IN-HOUSE ANTI BCMA CAR-T THERAPY FOR THE TREATMENT OF RELAPSED REFRACTORY MULTIPLE MYELOMA: PHASE 1 RESULTS.

HemaSphere, 2022
N. Asherie, S. Kfir-Erenfeld, B. Avni, S. Grisariu, M. Assayag, T. Sharon, E. Lebel, C. J. Cohen, M. E. Gatt, P. Stepensky   +9 more
doaj   +1 more source

Design and Synthesis of Peptide‐Polyester Conjugates for Cell‐Mediated Scaffold Degradation

Advanced Healthcare Materials, EarlyView.
This work describes polycaprolactone (PCL)‐based biomaterials engineered to degrade in response to cell‐secreted proteases. A fast‐degrading peptide (Fast) sequence is integrated into a PCL conjugate backbone to produce a biomaterial that is selectively degraded by multiple cell types compared to its scrambled control (ScrFast).
Korina Vida G. Sinad, Natasha K. Hunt, Srujan Singh, Kelly B. Seims, Yingjie Wu, E. Thomas Pashuck, Warren L. Grayson, Lesley W. Chow   +7 more
wiley   +1 more source

CO- TRANSPLANTATION OF BONE MARROW STROMAL CELLS WITH SCHWANN CELLS EVOKES MECHANICAL ALLODYNIA IN THE CONTUSION MODEL OF SPINAL CORD INJURY IN RATS [PDF]

Objective: Several studies have shown that, although transplantation of neural stem cells into the contusion model of spinal cord injury (SCI) promotes locomotor function and improves functional recovery, it induces a painful response, Allodynia ...
جغتایی, محمد تقی, پورحیدر, باقر, یکتا, زهرا, نجف زاده, نوروز, مهدی زاده, مهدی, بختیاری, مهرداد   +5 more
core  

Allogeneic bone marrow transplantation for children with histiocytic disorders: Use of TBI and omission of etoposide in the conditioning regimen

, 2003
The histiocytoses are rare disorders of antigen-processing phagocytic or antigen-presenting cells. Allogeneic bone marrow transplantation (BMT) can be curative of these disorders. We report a series of five children with Langerhans cell histiocytosis (n =
Cunningham, J. M., Handgretinger, R., Woodard, J. P., Leung, W., Hale, G. A., Bowman, L. C., Benaim, E., Heslop, H. E., Horwitz, E. M., Krance, R. A., Shearer, P. D.   +10 more
core   +1 more source

Dynamic International Prognostic Scoring System scores, pre-transplant therapy and chronic graft-versus-host disease determine outcome after allogeneic hematopoietic stem cell transplantation for myelofibrosis

Haematologica, 2012
Background Myelofibrosis is a myeloproliferative stem cell disorder curable exclusively by allogeneic hematopoietic stem cell transplantation and is associated with substantial mortality and morbidity. The aim of this study was to assess disease-specific
Markus Ditschkowski, Ahmet H. Elmaagacli, Rudolf Trenschel, Tanja Gromke, Nina K. Steckel, Michael Koldehoff, Dietrich W. Beelen   +6 more
doaj   +1 more source

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source

Rescue of myeloid lineage-committed preprogenitor cells from cytomegalovirus-infected bone marrow stroma [PDF]

, 1991
The effect of murine cytomegalovirus on myelopoiesis was studied in long-term bone marrow culture to find an in vitro correlate for the lethal virus interference with bone marrow reconstitution (W. Mutter, M. J. Reddehase, F. W. Busch, H.-J. Bühring, and
Busch, Friedrich W., Reddehase, Matthias J., Koszinowski, Ulrich H., Mutter, Wolfgang   +3 more
core