Results 51 to 60 of about 4,243,769 (269)
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Enhancing Human Resource Management System with Triangular Fuzzy Weighted Bonferroni Mean Operator
Malaysia Journal of Invention and Innovation, 2023 Organizations require an efficient human resource management system to manage employee-related matters such as attendance, leave, salaries, and training. The effectiveness of a business relies on how well it manages its human resources. To achieve this,
Noor Azzah Awang +2 more
doaj +2 more sources
International Journal of Computational Intelligence Systems, 2019 In recent times, to improve the interpretability and accuracy of computing with words processes, a rich linguistic representation model has been developed and referred to as Extended Comparative Linguistic Expressions with Symbolic Translation (ELICIT ...
Bapi Dutta +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
IEEE Access, 2022 The R-set is modeled by considering the risks associated with sources of information and future events. In the current work, there is no research on the aggregation operator of the R-set, and no in-depth research on its multi-attribute decision-making ...
Jianping Fan, Rui Cheng, Meiqin Wu
doaj +1 more source
Multiattribute Decision-Making Method with Intuitionistic Fuzzy Archimedean Bonferroni Means [PDF]
Mathematical Problems in Engineering, 2021 The Bonferroni mean (BM) can portray the inter-relationships among the arguments, which is based on algebraic norm. Archimedean norm is the generalization of algebraic norm. In this work, the intuitionistic fuzzy (IF) BMs on the basis of the Archimedean norm are investigated, including the Archimedean norm-based IF arithmetic BM (AN-IFABM) and the ...
openaire +2 more sources
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page +4 more
wiley +1 more source