Results 51 to 60 of about 3,982,620 (269)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

New q-Rung Orthopair Fuzzy Bonferroni Mean Dombi Operators and Their Application in Multiple Attribute Decision Making

open access: yesIEEE Access, 2020
Some q-rung orthopair fuzzy Bonferroni mean Dombi aggregation operators have been developed based on the Bonferroni mean, Dombi T-norm and T-conorm in q-rung orthopair fuzzy environment.
Wei Yang, Yongfeng Pang
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Triangular Fuzzy Partitioned Bonferroni Mean Operators and Their Application to Multiple Attribute Decision Making

open access: yes, 2020
© 2018 IEEE. The Bonferroni mean (BM) operator, introduced by Bonferroni, is a powerful tool to capture the interrelationship among aggregated arguments.
Merigó, JM, Verma, R, Mittal, N
core   +1 more source

Holm-Bonferroni-Hochberg and Benjamini-Hochberg corrections and Bayes factors of the correlation analyses between reading fluency and statistical learning measures.

open access: yes, 2023
Holm-Bonferroni-Hochberg and Benjamini-Hochberg corrections and Bayes factors of the correlation analyses between reading fluency and statistical learning measures.
Krisztina Sára Lukics (14833459)   +4 more
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

R-Set COPRAS (R-COPRAS) Methods-Based Multi-Attribute Decision-Making With RBM and RGBM Operators: A Case Study of Smart Mine Project Safety Assessment

open access: yesIEEE Access, 2022
The R-set is modeled by considering the risks associated with sources of information and future events. In the current work, there is no research on the aggregation operator of the R-set, and no in-depth research on its multi-attribute decision-making ...
Jianping Fan, Rui Cheng, Meiqin Wu
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Phon Mean oral history recording

open access: yes, 2001
An audio recording of an oral history of Phon Mean about fleeing Cambodia with her family at age ten and coming to the United States. She talks about life in Cambodia when she was a child and then about life in the U.S., including school, her first job ...
Mean, Phon
core   +1 more source

Distance measures, weighted averages, OWA operators and Bonferroni means

open access: yesApplied Soft Computing, 2017
We would like to thank the editor-in-chief, the associate editor and the anonymous reviewers for valuable comments that have improved the quality of the paper. Support from the project PIEF-GA-2011-300062 from the European Commission and from the University of Chile is gratefully ...
José M. Merigó   +2 more
openaire   +4 more sources

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