Results 121 to 130 of about 7,349 (211)

Transplantation of Autologous Bone Marrow Mesenchymal Stem Cells with Platelet-Rich Plasma Accelerate Distraction Osteogenesis in A Canine Model

open access: yesCell Journal, 2015
Objective: Distraction osteogenesis (DO) is a surgical procedure used to generate large volumes of new bone for limb lengthening. Materials and Methods: In this animal experimental study, a 30% lengthening of the left tibia (mean distraction distance:
Mohammad Mehdi Dehghan   +10 more
doaj  

The accordion technique did not improve bone healing in a mouse model of distraction osteogenesis

open access: yesScientific Reports
Distraction osteogenesis (DO) is a valuable surgical method for limb lengthening and bone defect correction, but its lengthy consolidation phase presents challenges.
David T. Bertrand   +7 more
doaj   +1 more source

Injuries in deep time: interpreting competitive behaviours in extinct reptiles via palaeopathology

open access: yesBiological Reviews, Volume 101, Issue 3, Page 1073-1090, June 2026.
ABSTRACT For over a century, palaeopathology has been used as a tool for understanding evolution, disease in past communities and populations, and to interpret behaviour of extinct taxa. Physical traumas in particular have frequently been the justification for interpretations about aggressive and even competitive behaviours in extinct taxa.
Maximilian Scott   +3 more
wiley   +1 more source

Lipomatosis From Prolonged Use of Corticosteroids in Ethiopia: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Lipomatosis is characterized by abnormal, localized fat overgrowth without associated fat loss. These growths are typically benign and follow specific distribution patterns. When induced by corticosteroids, this fat hypertrophy can occur in various locations, most commonly in the spinal epidural, retro‐orbital, and mediastinal spaces. Computed
Habtamu Mesele Gebray   +2 more
wiley   +1 more source

Measuring In‐Shoe Plantar Strain Outcomes in the Presence of Callus: A Preliminary Study Using the STAMPS3D Measurement System

open access: yesJournal of Foot and Ankle Research, Volume 19, Issue 2, June 2026.
ABSTRACT Introduction Diabetes‐related foot ulcers (DFU) are growing in prevalence, driven by the global rise in diabetes. Plantar callus has been identified as a risk factor for DFU formation, with its presence considered highly predictive for ulceration.
Francesca Sairally   +5 more
wiley   +1 more source

Pseudoaneurysm as an unusual complication in bone lengthening

open access: yesJPRAS Open
One of the risks of distraction osteogenesis-based techniques is the development of vascular complications, such as pseudoaneurysms associated with the osteotomies performed or the fixation elements of the external fixator used in the procedure ...
Javier Martínez Ros   +9 more
doaj   +1 more source

In Vivo Assessment of Distal Femur Fracture Motion via Weightbearing CT

open access: yesJournal of Orthopaedic Research, Volume 44, Issue 6, June 2026.
ABSTRACT Distal femur fractures have a significant risk of healing complications, with potentially suboptimal fracture motion. We developed an in vivo method of quantifying fracture motion to support translational research. Five men and one woman (age 48.3 ± 24.9 years; weight 79.8 ± 12.9 kg, mean ± SD) underwent non‐weightbearing and weightbearing CT ...
William D. Lack   +5 more
wiley   +1 more source

Harnessing energy metabolism for enhanced bone defect repair: Mechanisms and therapeutic strategies

open access: yesVIEW, Volume 7, Issue 3, June 2026.
This review addresses the critical challenge of bone defect repair by focusing on the underexplored role of cellular energy metabolism. It synthesizes regulatory mechanisms in bone‐forming cells and sums up innovative strategies—leveraging cell derivatives, active factors, and biomimetic scaffolds—to modulate metabolism for enhanced regeneration.
Junting Li   +5 more
wiley   +1 more source

Autopsy, deathways, and intercultural healthcare in the southern Peruvian Andes Autopsie, pratiques mortuaires et soins de santé interculturels dans le sud des Andes péruviennes

open access: yesJournal of the Royal Anthropological Institute, Volume 32, Issue 2, Page 456-473, June 2026.
While death remains a popular topic for anthropology, relatively few ethnographic accounts consider the modern bureaucratic processes accompanying it. One such process is public health autopsy, which scholars have largely taken for granted. Existing analysis has regarded it as a form of ‘cultural brokering’ and autopsy reluctance in communities is seen,
David M.R. Orr
wiley   +1 more source

Senescent BMSC‐Derived Thbs1 Drives Inflammaging and Impairs Bone Regeneration by Suppressing PINK1/Parkin‐Mediated Mitophagy in Macrophages

open access: yesAging Cell, Volume 25, Issue 6, June 2026.
Aging BMSC‐derived Thbs1 activates the macrophage TGF‐β/Smad3 pathway to transcriptionally repress Pink1, impairing mitophagy and causing mitochondrial ROS accumulation. This redox imbalance drives M1 polarization and IL‐6 secretion. IL‐6 feeds back to BMSCs via the JAK/STAT3 pathway to inhibit osteogenesis and upregulate Thbs1, establishing a self ...
Yifeng Xing   +15 more
wiley   +1 more source

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