Results 191 to 200 of about 841 (231)

First 20 Years of Orbitrap Mass Spectrometry as the Mainstream Analytical Technique

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT This review traces the first 20 years of Orbitrap mass spectrometry as a mainstream high‑resolution and accurate‑mass (HR/AM) technology. It outlines the historical development of the Orbitrap analyzer, the evolution of major instrument families, and the key technological innovations that enabled its widespread adoption. Particular emphasis is
Alexander Makarov
wiley   +1 more source

Chess in Mental Health: Therapeutic Potential and Neurocognitive Mechanisms—A Systematic Review

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT Objective Chess is an ancient game with simple rules but high cognitive demands. This review examined chess as a cognitive tool for patients with mental disorders and explored the cognitive mechanisms and neural structures that may underlie its effects. Method A systematic review of studies was conducted following PRISMA guidelines.
Maria Rodrigo‐Yanguas   +4 more
wiley   +1 more source

The Role of HUWE1 on Mouse Neural Cell Proliferation and Zebrafish Neurodevelopment

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT The HECT, UBA, and WWE domain‐containing E3 ubiquitin protein ligase 1 (HUWE1) gene is located on the X chromosome and has been implicated in neurodevelopmental disorders. However, the mechanisms by which HUWE1 dosage affects nervous system development remain poorly understood. In this study, we demonstrate that HUWE1 overexpression suppresses
Haojuan Wu   +10 more
wiley   +1 more source

Voice and Speech in Atypical Parkinsonian Disorders

open access: yesMovement Disorders Clinical Practice, EarlyView.
Background Motor speech disorders are early, common, and functionally limiting features of atypical parkinsonian disorders (APDs) such as progressive supranuclear palsy (PSP), corticobasal syndrome (CBS), and multiple system atrophy (MSA). These impairments are underrecognized and undertreated in neurology clinics.
Federico Rodriguez‐Porcel   +48 more
wiley   +1 more source

Resolution of Levodopa/Dopa‐Decarboxylase Inhibitor—Associated Microscopic Colitis with Subcutaneous Foslevodopa/Foscarbidopa: A Case Series and Review of the Literature

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Microscopic colitis (MC) typically presents with chronic, non‐bloody watery diarrhea. Diagnosis requires endoscopy with colonic mucosal biopsies. The etiology is multifactorial, with several medications implicated, although only a few cases have been attributed to oral levodopa/dopa‐decarboxylase inhibitor (LDDCI) therapy.
Romana Hintner   +10 more
wiley   +1 more source

Closing the Gate Before the Horse is out of the Barn: A Model to Effectively Predict the First Fall in Patients with Parkinson's Disease

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Most fall‐prediction models in Parkinson's disease (PD) rely on prior falls, limiting prevention. The Waiting Room of the Future (WROTF) platform collects standardized motor and cognitive measures during routine visits, integrated into electronic health records (EHR).
Saar Anis   +5 more
wiley   +1 more source

Weak Solutions for a Class of Nonlocal Singular Problems Over the Nehari Manifold

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT In this paper, we consider a nonlocal model of dilatant non‐Newtonian fluid with a Dirichlet boundary condition. By using the Nehari manifold and fibering map methods, we obtain the existence of at least two weak solutions, with sign information.
Zhenfeng Zhang   +2 more
wiley   +1 more source

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