Results 91 to 100 of about 592,133 (314)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Towards a methodology for optimizing indicator indicators of the working process of diesel locomotive diesel engines [PDF]

open access: yesE3S Web of Conferences
A methodology is proposed for substantiating the optimal parameters of the turbocharger and air cooler of a two-stroke diesel locomotive diesel engine with air supercharging when its diesel generator set operates in partial modes.
Ablyalimov Oleg
doaj   +1 more source

Retificador monofásico com fator de potência unitário, de alto ganho, baseado em um conversor boost híbrido [PDF]

open access: yes, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Elétrica, Florianópolis, 2013Este trabalho apresenta uma nova topologia de retificador monofásico de elevado fator de potência ...
Maccarini, Marcello Costa
core  

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

How Obama's backing for NBA Africa venture could boost basketball on the continent [PDF]

open access: yes, 2021
First paragraph: Former US president Barack Obama’s decision to invest in the National Basketball Association’s Africa venture reflects a lot about his past – his basketball playing youth and his African roots.
Nauright, John, Zipp, Sarah
core  

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Dokters van de Wereld, ook in Antwerpen : 'Gezondheidszorg is een mensenrecht'

open access: yes, 2023
: Dokters van de Wereld vind je niet langer alleen in buitenlandse noodsituaties. Ook in Antwerpen-Noord helpen ze mensen die geen toegang krijgen tot reguliere zorg.
Boost, Didier
core   +1 more source

High-risk prostate cancer treated with a stereotactic body radiation therapy boost following pelvic nodal irradiation

open access: yesFrontiers in Oncology
PurposeModern literature has demonstrated improvements in long-term biochemical outcomes with the use of prophylactic pelvic nodal irradiation followed by a brachytherapy boost in the management of high-risk prostate cancer.
Jonathan W. Lischalk   +11 more
doaj   +1 more source

Boosting

open access: yes, 2012
An accessible introduction and essential reference for an approach to machine learning that creates highly accurate prediction rules by combining many weak and inaccurate ones. Boosting is an approach to machine learning based on the idea of creating a highly accurate predictor by combining many weak and inaccurate “rules of thumb.” A
Schapire, Robert E., Freund, Yoav
openaire   +2 more sources

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

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