Results 61 to 70 of about 317,195 (260)

Feasibility of Dose Escalation in Patients With Intracranial Pediatric Ependymoma

Frontiers in Oncology, 2019
Background and purpose: Pediatric ependymoma carries a dismal prognosis, mainly owing to local relapse within RT fields. The current prospective European approach is to increase the radiation dose with a sequential hypofractionated stereotactic boost. In
Fatima Tensaouti, Fatima Tensaouti, Anne Ducassou, Léonor Chaltiel, Stéphanie Bolle, Jean Louis Habrand, Claire Alapetite, Bernard Coche-Dequeant, Valérie Bernier, Line Claude, Christian Carrie, Laetitia Padovani, Xavier Muracciole, Stéphane Supiot, Aymeri Huchet, Julie Leseur, Christine Kerr, Grégorie Hangard, Albert Lisbona, Farid Goudjil, Régis Ferrand, Anne Laprie, Anne Laprie, Anne Laprie   +23 more
doaj   +1 more source

Validity and feasibility of remote measurement systems for functional movement and posture assessments in people with axial spondylarthritis

Healthcare Technology Letters, 2022
Introduction: This study aimed to estimate the criterion validity of functional movement and posture measurement using remote technology systems in people with and without Axial spondylarthritis (axSpA).
Erin Hannink, Maedeh Mansoubi, Neil Cronin, Benjamin Wilkins, Ali A. Najafi, Benjamin Waller, Helen Dawes   +6 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

A Family of Scalable Non-Isolated Interleaved DC-DC Boost Converters With Voltage Multiplier Cells

IEEE Access, 2019
In this paper, a family of non-isolated interleaved high-voltage-gain DC-DC converters is presented. This family can be used in a wide variety of applications, such as in a photovoltaic systems interface to a high voltage DC distribution bus in a ...
Ahmad Alzahrani, Mehdi Ferdowsi, Pourya Shamsi   +2 more
doaj   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Towards a methodology for optimizing indicator indicators of the working process of diesel locomotive diesel engines [PDF]

E3S Web of Conferences
A methodology is proposed for substantiating the optimal parameters of the turbocharger and air cooler of a two-stroke diesel locomotive diesel engine with air supercharging when its diesel generator set operates in partial modes.
Ablyalimov Oleg
doaj   +1 more source

Boosting Performance [PDF]

Sports Health: A Multidisciplinary Approach, 2021
openaire   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source