Results 61 to 70 of about 1,217,759 (290)
Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz +12 more
wiley +1 more source
In early 2021, the primary vaccination campaign against COVID-19 was rolled out to the adult population in Belgium, followed by the first booster campaign towards the end of the year.
T. Braeye +7 more
core
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani +7 more
wiley +1 more source
Dose calculations for [131I] meta-iodobenzylguanidine-induced bystander effects
Targeted radiotherapy is a potentially useful treatment for some cancers and may be potentiated by bystander effects. However, without estimation of absorbed dose, it is difficult to compare the effects with conventional external radiation treatment ...
R. J. Mairs +17 more
core +1 more source
Correlates of protection for booster doses of the BNT162b2 vaccine
Abstract Variants of concern (VOC) of SARS-CoV2 and waning immunity pose a serious global problem. Overall, vaccination and prior infection appear to provide significant protection to the majority of individuals, but some remain susceptible to infection and severe disease.
Tomer Hertz +25 more
openaire +2 more sources
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben +4 more
wiley +1 more source
Background: Exposure to new COVID-19 variants and decline in herd immunity may result in new or repeat infection. The booster dose may face certain challenges that result in low uptake.
Nikita Sharma, Meenal Madhukar Thakare
doaj +1 more source
Sports medicine Booster doses are not needed [PDF]
EDITOR, - J C M Sharp's advice on tetanus immunisation1 is contrary to that specified in the current edition of the “green book.” For immunised adults who have received five doses of tetanus vaccine, either as children or according to the recommended schedule of immunisation for those aged 10 years and over, booster doses are not recommended, other ...
openaire +1 more source
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk +10 more
wiley +1 more source
Infants born to HBsAg/HBeAg-positive mothers remain risk for hepatitis B virus vaccine breakthrough infection (VBI). In this multicenter prospective cohort study, we assessed whether increased neonatal vaccine dose (20 μg vs.
Yuchen Pan +8 more
doaj +1 more source

