Results 251 to 260 of about 22,043,161 (356)

Goodness-of-fit tests for Markovian time series models: Central limit theory and bootstrap approximations [PDF]

, 2008
Michael H. Neumann, Efstathios Paparoditis   +1 more
openalex   +1 more source

A Joint Pharmacometric Model of Iohexol and Creatinine Administered through a Meat Meal to Assess GFR and Renal OCT2/MATE Activity

Clinical Pharmacology &Therapeutics, EarlyView.
Accurately assessing glomerular filtration rate (GFR) from plasma creatinine concentrations is challenging in patients with unstable renal function. This study aimed to refine the understanding of creatinine kinetics for more reliable assessments of GFR and net creatinine tubular secretion (nCTS) via OCT2/MATE in humans.
Zhendong Chen, Qian Dong, Charalambos Dokos, Jana Boland, Uwe Fuhr, Max Taubert   +5 more
wiley   +1 more source

Statistical and reliability analysis of communication disability severity in Saudi Arabia using novel probability distribution. [PDF]

Sci Rep
Al-Essa LA, Ali Al-Shamiri MM, A Almazah MM, Hamdoon FM.   +3 more
europepmc   +1 more source

Analysis of Heat Wave Effects on Health by Using Generalized Additive Model and Bootstrap-Based Model Selection [PDF]

, 2008
Francesco Pauli, Laura Rizzi
openalex   +1 more source

Modeling and Simulation to Inform Apixaban Dosing in Pediatrics With Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma Treated With Asparaginase

Clinical Pharmacology &Therapeutics, EarlyView.
Apixaban could be a potential treatment option for the prevention of venous thromboembolism (VTE) in children with acute lymphoblastic leukemia (ALL) or lymphoblastic lymphoma (LL). This analysis describes an updated two‐compartment population pharmacokinetic (PPK) model that characterizes the PK variability of apixaban in pediatric patients with ALL ...
Praneeth Jarugula, Toni Ajavon‐Hartmann, Obinna Obianom, Elizabeth Ludwig, Christina Crevar, David Marchisin, Zhaoqing Wang, Weidong Chen, Bing He, Lesley G. Mitchell, Vilmarie Rodriguez, Glen Lew, Vidya Perera, Bindu Murthy, Samira Merali   +14 more
wiley   +1 more source

Evaluating Change in Adjusted <i>R</i>-Square and <i>R</i>-Square Indices: A Latent Variable Method Application. [PDF]

Educ Psychol Meas
Raykov T, DiStefano C.
europepmc   +1 more source

Alemtuzumab Exposure and T Lymphocyte Depletion: A Population Pharmacokinetic‐Pharmacodynamic Model of Alemtuzumab Induction Therapy for Kidney Transplantation

Clinical Pharmacology &Therapeutics, EarlyView.
Alemtuzumab is a T cell‐depleting monoclonal antibody that is used for the prevention of kidney transplant rejection. The duration of lymphodepletion after the current standard induction therapy dose is likely longer than necessary, resulting in prolonged T cell lymphopenia with the associated risk of infections. Here, the interplay between alemtuzumab
Lukas K. van Vugt, Tom C. Zwart, Suzanne Bezstarosti, Sebastiaan Heidt, Marlies E. J. Reinders, Dennis A. Hesselink, Aiko P. J. de Vries, Brenda C. M. de Winter, Dirk Jan A. R. Moes   +8 more
wiley   +1 more source

Prognostic Value of Minnesota Multiphasic Personality Inventory-2 (MMPI-2) Profiles in Predicting Outcomes of Occipital Nerve Stimulation for Refractory Chronic Migraine: A Retrospective Bias-Corrected Multivariable Analysis. [PDF]

Curr Pain Headache Rep
Mercieri M, Leoni MLG, Naccarato A, Viswanath O, Sarmi SSA, Varrassi G, Cascella M, Arcioni R.   +7 more
europepmc   +1 more source

Parametric bootstrap approximation to the distribution of EBLUP and related prediction intervals in linear mixed models [PDF]

, 2008
Snigdhansu Chatterjee, Partha Lahiri, Huilin Li   +2 more
openalex   +1 more source

Use of PopPK and E‐R Analyses toward Explaining Causal Link Between ADAMTS13 in Recombinant vs. Plasma‐Based Therapies and Clinical Effects in cTTP

Clinical Pharmacology &Therapeutics, EarlyView.
Congenital thrombotic thrombocytopenic purpura (cTTP) is an ultra‐rare, potentially life‐threatening condition caused by a deficiency of the blood enzyme ADAMTS13. Until now, ADAMTS13 replacement has been achieved with infusions of plasma or plasma‐based therapies (PBT).
Munjal Patel, Huijuan Xu, Olivier Barriere, Paul Diderichsen, Parth Patwari, Andy Z. X. Zhu, Jean François Marier, Thomas Peyret, Linda T. Wang, Björn Mellgård, Wenping Wang, Indranil Bhattacharya   +11 more
wiley   +1 more source