Results 191 to 200 of about 2,284,562 (345)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Critical Infrastructure Exposure and Gray-Zone Infiltration Along the Southern U.S. Border (2021–2025): A Multi-Domain Threat Assessment

Nicolin Decker
openalex   +1 more source

Distant neighbours. Economic adjustment processes at the Finnish-Russian border [PDF]

For decades, the closed East/West border was an effective barrier for cross-border interaction at a local and regional level. It was reflected, among other things, in production structures and settlement patterns in the border regions. Since around 1990,
Eskelinen, Heikki, Niiranen, Kimmo
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Cross-border vaccination behaviour of residents living in a European Union border region: a cross-sectional survey study. [PDF]

BMC Glob Public Health
Huijten DCM, Widdershoven V, Paardekooper S, Hoebe CJPA, Reijs RP.   +4 more
europepmc   +1 more source

The customary land tenure system and women's access to land in Bipare and Kafinarou : border area between northern Cameroon and the south west of Chad

, 2008
Babette Koultchoumi
openalex   +1 more source

FIGURE 8 in Lecithoceridae (Lepidoptera: Gelechioidea) from Nimba Mts. bordering Liberia and Guinea, Part I: The subfamily Torodorinae, with descriptions of 15 new species

Karisch, Timm, Dutton, Amy-Jayne, Yu, Tae-Uk, Park, Kyu-Tek   +3 more
openalex   +1 more source

Transcarpathia – Ukrainian border region at the edge of the EU. Internal and external representations [PDF]

, 2013
Peter Jordan
openalex   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Entwined economies of violence: understanding borderland conflict and resource politics in northern Kenya. [PDF]

Disasters
Rogei DS.
europepmc   +1 more source