Results 31 to 40 of about 2,308,949 (362)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Factors associated with diabetic foot among type 2 diabetes in Northern area of Saudi Arabia: a descriptive study

BMC Research Notes, 2019
Objective Foot complications are considered to be a devastating consequence of type 2 diabetes mellitus (T2DM), posing a major medical and economic burden.
Manal S. Fawzy, Mariam A. Alshammari, Ashwaq A. Alruwaili, Rehab T. R. Alanazi, Jewaher A. M. Alharbi, Abdulaziz Mohammed R. Almasoud, Reem A. Alshammari, Eman A. Toraih   +7 more
doaj   +1 more source

Use of ePortfolios to improve English speaking skills by learners of English as a foreign language

Vivat Academia, 2022
High-impact practices (HIPs) have been adopted by many universities around the world to enhance student learning. The aim of this qualitative study is to analyze how building ePortfolios may impact the student learning experience via weekly reflections.
Elias Bensalem, Fahad Hamed Alenazi
doaj   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Self-medication with antibiotics and awareness of antibiotic resistance among population in Arar city, Saudi Arabia

Journal of Infection in Developing Countries, 2022
Introduction: Self-medication with pharmaceutical products can be defined as the use of these products without a medical prescription, and the production, distribution, and sale of these products are the client’s responsibility, while they think it is ...
Elhassan Hussein Eltom, Abdallah Lafi Alanazi, Jamal Farhan Alenezi, Ghazi Meshal Alruwaili, Abdulaziz Mohammed Alanazi, Rahma Hamayun   +5 more
doaj   +1 more source

On degeneration of tensors and algebras [PDF]

, 2016
An important building block in all current asymptotically fast algorithms for matrix multiplication are tensors with low border rank, that is, tensors whose border rank is equal or very close to their size.
Bläser, Markus, Lysikov, Vladimir
core   +2 more sources

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Computing Border Bases without using a Term Ordering

, 2011
Border bases, a generalization of Groebner bases, have actively been researched during recent years due to their applicability to industrial problems. A. Kehrein and M.
Kaspar, Stefan
core   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Gender-based Morphometric Analysis of the Human Orbital Aperture Profile using 3D Reconstruction Computed Tomography: A Cross-sectional Retrospective Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Sex estimation is a crucial aspect of forensic medicine and requires primary consideration when examining skeletal remains. Among the various anatomical features, the orbital region holds significant importance due to its distinct ...
Muhammad Omer Afzal Bhatti, Mujeeb Ur Rehman Parrey, Muhammad Ikram Ali, Allah Rakhyo Shoro, Abdulkrem Ahmed Alenazi, Rayan Alhumaidi Alruwaili   +5 more
doaj   +1 more source