Results 141 to 150 of about 639,593 (286)

Clinicopathologic Features of Antibrush Border Antibody Disease

Kidney International Reports
Introduction: Antibrush border antibody disease (ABBA) is an autoimmune tubulointerstitial kidney disease that primarily affects older individuals and results in progressive kidney failure. It is rare with only 20 reported cases. Here, we describe a case
Joel D. Murphy, Tiffany N. Caza, Clarissa A. Cassol, Aaron Storey, Josephine M. Ambruzs, Christie Boils, Patrick D. Walker, Shree Sharma, Nidia Messias, Randolph Hennigar, Nicole K. Andeen, Christine VanBeek, Matthew Palmer, Lakshna Sankar, Pooja Sanghi, Kumar Dinesh, Lance Dicker, Anatoly Urisman, Christopher P. Larsen   +18 more
doaj   +1 more source

Distribution and Genetic Characterization of Border Disease Virus Circulating in Sardinian Ovine Flocks. [PDF]

Pathogens, 2020
Piras IM, Dei Giudici S, Fadda M, Anfossi AG, Oggiano A, Pittau M, Chessa B.   +6 more
europepmc   +1 more source

An Assessment of Economic Losses due to Avian Flu in Manipur State [PDF]

The impact of 2007 outbreak of avian flu in the state of Manipur has been reported. The loss due to the disease has been found to be 14 per cent of the total value of livestock outputs in the entire state. More than 3 lakh birds were culled and 24 tonnes
Datta, K.K., Joshi, P.K., Kumar, B. Ganesh, Singh, S.B.   +3 more
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Reversed Immunoglycomics Identifies α‑Galactosyl-Bearing Glycotopes Specific for Leishmania major Infection

JACS Au, 2021
Alba L. Montoya, Victoria M. Austin, Susana Portillo, Irodiel Vinales, Roger A. Ashmus, Igor Estevao, Sohan R. Jankuru, Yasser Alraey, Waleed S. Al-Salem, Álvaro Acosta-Serrano, Igor C. Almeida, Katja Michael   +11 more
doaj   +1 more source

Osteochondral fragments in the metacarpo- and metatarsophalangeal joint and their clinical importance [PDF]

, 2011
The radiographic evaluation of the fetlock joint as part of a lameness or prepurchase examination often reveals osteochondral fragmentation. These fragments can either be causing lameness or have no clinical importance at the time of examination. However,
Declercq, Jeroen, Hauspie, Stijn, Martens, Ann, Saunders, Jimmy   +3 more
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source