Results 111 to 120 of about 1,568,330 (293)
EdukasiaIn real life, the economy is open and continuously developing, so in its learning, critical thinking skills are needed to make it easier to understand.
Ari Data +2 more
doaj +1 more source
Komplexitätsdenken und Grenzforschung. Überlegungen und Perspektiven zu einem vielversprechenden Verhältnis [PDF]
Despite the increased discourse on the complexity of borders, there are hardly any references in the academic debate as to what exactly complex borders mean or complexity-oriented border research.
WILLE, Christian
core +1 more source
Molecular Oncology, EarlyView.Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis +20 more
wiley +1 more source
Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Mednarodno Inovativno PoslovanjeThis case study examines the impact of cross-border business curriculum design in the Slovenian-Italian border region, focusing on a MA-level program in Intercultural Management delivered in the twin cities of Nova Gorica (Slovenia) and Gorizia (Italy ...
Svitlana Buko, Giustina Selvelli
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Transdisciplinary thinking for conceptualising borders and boundaries [PDF]
, 2021 The chapters included in this section invite reflections and pave the road for discussing various notions of borders and boundaries as they manifest in architecture, urbanism, and the overall built environment of contemporary societies. In essence, they address key issues present themselves as manifestations of borders and boundaries as debated in the ...
openaire +3 more sources
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source