Results 151 to 160 of about 194,453 (352)

Bio‐Based Amphiphilic Farnesyl Glycidyl Ether Block Copolymers: Aqueous Self‐Assembly and Solubilization Boosting

open access: yesChemistry – A European Journal, EarlyView.
Bio‐derived amphiphilic poly(ethylene glycol)‐b‐poly(terpenyl glycidyl ether) diblock copolymers (mPEG114‐b‐PTGEm) were synthesized via AROP from farnesyl glycidyl ether (FarGE) and its hexahydrogenated derivative (HHFarGE). Block copolymer amphiphilicity is easily tunable via the TGE block size m and systematically affects the critical micelle ...
Maximilian Krappel   +6 more
wiley   +1 more source

The third-wave of cognitive-behavioral therapies for borderline personality disorder in Iran: a systematic review [PDF]

open access: yesفصلنامه ابن سینا, 2019
Background: Among personality disorders, borderline personality disorder is one of the severe and serious psychiatric disorders, and one of the most effective psychological treatments to improve its symptoms is third-wave psychotherapies.
Fateme Moeeni   +2 more
doaj  

Functional regression with intensively measured longitudinal outcomes: a new lens through data partitioning

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract Modern longitudinal data from wearable devices consist of biological signals at high‐frequency time points. Distributed statistical methods have emerged as a powerful tool to overcome the computational burden of estimation and inference with large data, but methodology for distributed functional regression remains limited.
Cole Manschot, Emily C. Hector
wiley   +1 more source

Clinical effectiveness and treatment satisfaction between two triple‐therapy regimens in treating neuropathic pain: A real‐world data

open access: yesIbrain, EarlyView., 2023
This study compared the clinical effectiveness and treatment satisfaction of Pregabalin and Gabapentin triple therapy for neuropathic pain in a real‐world setting. The primary outcome measured the reduction in mean Self‐Administered Leeds Assessment of Neuropathic Symptoms and Signs pain score value from baseline to 12 weeks posttreatment.
Nithya Raju   +7 more
wiley   +1 more source

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Ascending Doses and Dose Titration of Bexicaserin in Healthy Participants in a Randomized, Double‐Blind, Placebo‐Controlled Study

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Bexicaserin (LP352) is a selective superagonist of the 5‐hydroxytryptamine 2C (5‐HT2C) receptor currently in development for the treatment of seizures that arise from developmental and epileptic encephalopathies. This phase 1, double‐blind, placebo‐controlled multiple ascending dose (MAD) study assessed the safety, tolerability, and ...
Jonathan Williams   +7 more
wiley   +1 more source

Drug‐Induced QT Prolongation: Associations Between Risk Classifications in a Swedish Clinical Decision Support System and Clinical Outcomes

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Potential adverse drug events can be signaled in Clinical Decision Support Systems (CDSSs). This study validated a Swedish CDSS (Janusmed Risk Profile) by investigating associations between calculated risk classifications of drugs with QT‐prolonging potential and registered related clinical outcomes.
Ola Nordqvist   +6 more
wiley   +1 more source

Quality of life, burden and emotion regulation difficulties in relatives of borderline personality disorder patients. [PDF]

open access: yes, 2019
Treball Final de Grau en Psicologia. Codi: PS1048. Curs: 2018/2019Borderline Personality Disorder (BPD) is a mental disorder characterized by dominant patterns of emotional instability, in addition to presenting alterations of self-image, instability in
Pujol Edo, Laura
core  

Fifty years of research on the Joulters ooid sandbody—Impact on carbonate sedimentology and diagenesis and lessons learned from an invaluable analogue

open access: yesThe Depositional Record, EarlyView.
The Joulters ooid sandbody of northern Great Bahama Bank is a vast expanse of muddy ooid sands partly rimmed by clean ooid sands and formed into a relatively thick layer of significant extent. Knowledge of the development of depositional and diagenetic patterns in the Joulters example has forwarded our general understanding of carbonate sedimentology ...
Paul (Mitch) Harris
wiley   +1 more source

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