Results 91 to 100 of about 278,522 (247)

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Impact of Dose Titration Using the Seizure Quality Rating (SQR) Scale on Electroconvulsive Therapy (ECT) Outcomes: A Quality Improvement Project

open access: yesBJPsych Open
Aims: This Quality Improvement Project (QIP) aimed to assess the impact of incorporating the Seizure Quality Rating (SQR) scale into ECT dose titration practices.
Mohsin Nazeer Muhammed   +1 more
doaj   +1 more source

The impact and challenges of sustainable biogas implementation: moving towards a bio-based economy

open access: yesEnergy, Sustainability and Society, 2017
Background Engineers face increasing pressure to manage and utilize waste (whether of animal, human or municipal origin) in a sustainable way. We suggest that a solution to the problem of organic waste in rural communities lies in their being able to ...
Ralph Muvhiiwa   +4 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Borders in Globalization: Project update 2016-2017 [PDF]

open access: yes, 2017
Since reporting on the first two years of our grant at the end of 2015, BIG has continued to implement its ambitious research agenda across all six areas of study.
Borders in Globalization
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Researching borders. Capturing social imaginary through "maps and map-making" [PDF]

open access: yes, 2010
Grosse Kettler S. Researching borders. Capturing social imaginary through "maps and map-making". COMCAD Arbeitspapiere - working papers, 81.
Grosse Kettler, Sabrina
core  

The RESILIENT Dataset: Multimodal Monitoring of Ageing-Related Comorbidities and Cognitive Decline

open access: yesScientific Data
The growing ageing population and prevalence of comorbidities pose significant healthcare challenges, from increasing hospitalisations to dementia risk.
Nathalia Céspedes Gómez   +14 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

A Re-Audit of Physical Health Monitoring of Day-Care Patients in the Adult Eating Disorder Service at Surrey and Borders Partnership NHS Foundation Trust

open access: yesBJPsych Open
Aims To determine if the physical health monitoring of day-care patients in the Adult Eating disorder service (AEDS) is done in line with the recommendations of NICE guidelines and relevant Medical Emergencies in Eating Disorders (MEED) Guidance on ...
Amit Fulmali, Tayeem Pathan
doaj   +1 more source

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