Results 41 to 50 of about 5,538,102 (159)

Sex‐dependent effects of a high‐fat diet‐induced obesity model on cerebrovascular health and brain metabolism

Experimental Physiology, EarlyView.
Abstract Mid‐life obesity is a major risk factor for neurodegenerative diseases, with mitochondrial and cerebrovascular dysfunction considered key mediators. Lysine acetylation is a reversible post‐translational modification that regulates several mitochondrial metabolic and biochemical processes.
Nicole N. Eminhizer, Dena Lin, Alec Hanshew, Jackson Stewart, Steven Ball, Christa Lilly, Saina S. Prabhu, Kate Karelina, Eric E. Kelley, Randy W. Bryner, Dharendra Thapa, Paul D. Chantler   +11 more
wiley   +1 more source

Low Levels of Branched Chain Amino Acids, Eicosapentaenoic Acid and Micronutrients are Associated with Low Muscle Mass, Strength and Function in Community-Dwelling Older Adults

The Journal of Nutrition, Health & Aging, 2018
BackgroundSarcopenia, the age-related decrease in muscle mass and function can result in adverse health outcomes and subsequent loss of independence. Inadequate nutrition is an important contributor to the aetiology of sarcopenia, and dietary strategies ...
S. T. Borg, Y. Luiking, A. V. Helvoort, Y. Boirie, Jos M. G. A. Schols, C.P.G.M. de Groot   +5 more
semanticscholar   +1 more source

Pulmonary arterial mechanoreceptors modulate exercise‐induced sympathetic activation in healthy humans during moderate‐intensity hypoxic exercise

The Journal of Physiology, EarlyView.
Abstract figure legend This randomized cross‐over trial (N = 12) addressed the hypothesis that selective reduction of pulmonary arterial pressure (i.e. manipulation of pulmonary arterial mechanoreceptor activation) during hypoxic exercise would reduce sympathetic outflow (muscle sympathetic nerve activity (MSNA)) in healthy humans.
Michiel T. Ewalts, Thomas D. Griffiths, Andrew J. M. Douglas, Elliott J. Jenkins, Guto Wyn Hughes, Craig D. Steinback, Lydia L. Simpson, Samuel J. Oliver, Mike Stembridge, Jonathan P. Moore   +9 more
wiley   +1 more source

Gas exchange and pulmonary stress variations during SCUBA and breath‐hold diving in open seawater

The Journal of Physiology, EarlyView.
Abstract figure legend Healthy, trained divers were studied before, during and after diving in open seawater with different techniques. SCUBA divers (diving to 15 or 40 m with air; cycling at depth) and breath‐hold divers (BHDs; sled‐assisted dives to 15, 25 or 40 m) underwent underwater and surface arterial blood gas (ABG) sampling.
Matteo Paganini, Tommaso Antonio Giacon, Simona Mrakic‐Sposta, Luca Martani, Danilo Cialoni, Lorenzo Zucchi, Vincenzo Maffei, Rosario Cifali, Mariano Marmo, Enrico M Camporesi, Richard E Moon, Gerardo Bosco   +11 more
wiley   +1 more source

Resting lung volume phenotypes in COPD: implications for exertional dyspnoea and exercise tolerance

ERJ Open Research
Background Lung volumes and dyspnoea vary markedly at a given forced expiratory volume in 1 s in COPD. We aim to investigate whether hyperinflation (high total lung capacity (TLC)) adds value to simpler inspiratory capacity (IC) in predicting mechanical ...
Danilo C. Berton, Abed A. Hijleh, Fernanda O. Silva, Diogo Oliveira, Karam Alosta, Guilherme D. Back, Alessandro Porcella, Reginald M. Smyth, Matthew D. James, Nicolle J. Domnik, Denis E. O'Donnell, J. Alberto Neder   +11 more
doaj   +1 more source

Direct Policy Search for a Risk‐Based Levee Design Framework With Scenario Reduction

Journal of Flood Risk Management, Volume 19, Issue 3, September 2026.
ABSTRACT Risk‐based management of coastal flood risk using realistic, process‐based models poses computational challenges, particularly when addressing uncertainties like sea‐level rise. This study explores the use of direct policy search (DPS) as a state‐dependent, adaptive decision‐making approach for upgrading levee systems.
Jingya Wang, David R. Johnson
wiley   +1 more source

Characterization of BRCA1 and BRCA2 Deleterious Mutations and Variants of Unknown Clinical Significance in Unilateral and Bilateral Breast Cancer: The WECARE Study

Human Mutation, 2010
BRCA1 and BRCA2 screening in women at high‐risk of breast cancer results in the identification of both unambiguously defined deleterious mutations and sequence variants of unknown clinical significance (VUS).
Å. Borg, Robert W. Haile, K. Malone, M. Capanu, A. Diep, Therese Törngren, S. Teraoka, C. Begg, Duncan C. Thomas, P. Concannon, L. Mellemkjaer, L. Bernstein, Lina Tellhed, Shanyan Xue, E. Olson, X. Liang, Jessica Dolle, A. Børresen-Dale, J. Bernstein   +18 more
semanticscholar   +1 more source

The Vulnerable on Campus: Financial Independence of College Students

Journal of Consumer Affairs, Volume 60, Issue 3, Fall 2026.
ABSTRACT College years are a critical transition period from financial dependence to financial independence for young adult college students but research on financial independence of this population is limited. The purpose of this exploratory, mixed‐method study is to identify types of young adult college students in terms of financial independence ...
Jing Jian Xiao, Nilton Porto, Luiz Cruz, Ting An   +3 more
wiley   +1 more source

Motivational Coaching Cues Can Modulate Prefrontal Cortex Activity and Perceptual Responses of Elite Football Players During High‐Intensity Interval Training: A Randomised Crossover fNIRS Study

European Journal of Sport Science, Volume 26, Issue 8, August 2026.
ABSTRACT Football coaches commonly provide verbal encouragement and exercise end‐point feedback to sustain players' effort by enhancing motivation during fitness training such as high‐intensity interval training (HIIT). However, the influence of such cues on the prefrontal cortex (PFC), a region involved in exercise cessation decisions, remains unclear.
Sanghyuk Han, SoYoung Ahn, Yunho Sung, Ji‐won Seo, Xinxing Li, Seungoh Han, Chaewoon Kim, Wook Song   +7 more
wiley   +1 more source

Vertical Correlation Lengths as a Tool for Quantifying Profiling Capabilities in the Planetary Boundary Layer and Troposphere and Defining Future Requirements

Earth and Space Science, Volume 13, Issue 8, August 2026.
Abstract The planetary boundary layer (PBL) is the portion of the troposphere that is directly influenced by the presence of the Earth's surface. The thermodynamic structure of this layer exhibits a wide variety of characteristics across the globe. In 2018 the National Academies of Sciences, Engineering, and Medicine Space Studies Board recommended ...
M. L. Loveless, R. O. Knuteson, D. M. Loveless, T. Wagner   +3 more
wiley   +1 more source