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Boric Acid, a Lewis Acid With Unique and Unusual Properties: Formulation Implications [PDF]
This review provides insight into the use of boric acid as a pharmaceutical, a buffer, and an adjuvant/excipient in pharmaceutical formulations. Boric acid is a Lewis acid with a pKa of 8.92–9.24 that is sensitive to temperature, ionic strength, and ...
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Boric Acid Poisoning in an Infant
New England Journal of Medicine, 1958THIS report is made to re-emphasize the hazards of using boric acid as an antiseptic and leaving drugs in dangerous areas.
J P, CONNELLY +2 more
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Transcutaneous absorption of boric acid
The Journal of Pediatrics, 1953Summary 1. Three case of transcutaneous absorption of boric acid in infants treated for diaper rash are reported. One child died. The diagnoses were made on clinical grounds and corroborated by laboratory analysis of blood, urine, and cerebrospinal fluid. 2.
J, DUCEY, D B, WILLIAMS
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Acute ingestions of boric acid
Journal of Toxicology: Clinical Toxicology, 1986Four patients with elevated serum boric acid levels after single, acute ingestions of 10 to 297 grams were reported to the Rocky Mountain Poison and Drug Center (RMPDC) between January 1983 and August 1985. Systemic effects were absent. In 1983-4, 364 cases of boric acid exposure were reported to the RMPDC with only one fatality from a probable chronic
C H, Linden +3 more
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Journal of the American Medical Association, 1945
Many indispensable drugs are known to be dangerous when used in improper dose or by unusual routes of administration—digitalis, iodine and others immediately come to mind as illustrations. Certain toxic drugs— arsenicals, for example—continue in use because of their effectiveness and because nontoxic substitutes of proved effectiveness are lacking.
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Many indispensable drugs are known to be dangerous when used in improper dose or by unusual routes of administration—digitalis, iodine and others immediately come to mind as illustrations. Certain toxic drugs— arsenicals, for example—continue in use because of their effectiveness and because nontoxic substitutes of proved effectiveness are lacking.
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A.M.A. Archives of Dermatology, 1956
The last decade has seen the development of a large number of therapeutic agents for use in skin diseases. Some are highly potent and specific and when applied for a particular bacterial infection are more effective than any other agent. The nonspecificity of the vast majority of dermatidides, their nature being influenced perhaps more by the host ...
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The last decade has seen the development of a large number of therapeutic agents for use in skin diseases. Some are highly potent and specific and when applied for a particular bacterial infection are more effective than any other agent. The nonspecificity of the vast majority of dermatidides, their nature being influenced perhaps more by the host ...
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Chelation of boric acid with nitropyrocatechols and the photometric determination of boric acids
Analytical Chemistry, 1972E J, Hakoila, J J, Kankare, T, Skarp
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Pure Boric Acid Does Not Show Room‐Temperature Phosphorescence (RTP)
Angewandte Chemie - International Edition, 2022Zhu Wu +2 more
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