Results 231 to 240 of about 960,199 (321)

Adenine nucleotide translocator and ATP synthase cooperate in mediating the mitochondrial permeability transition

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Both ATP synthase and adenine nucleotide translocator (ANT) play key roles in mediating the permeability transition. The contribution of ANT becomes evident in the presence of atractylate (ATR) at pH 6.5, a condition that prevents ATP synthase channel activity. At pH 7.4, this effect is minimal, suggesting a critical role for ATP
Ludovica Tommasin   +7 more
wiley   +1 more source

Blebbistatin reduces calcium buffering in cardiomyocytes: Consequences for cellular electrophysiology

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Blebbistatin reduces Ca2+ buffering in induced pluripotent stem cell‐derived atrial cardiomyocytes. Blebbistatin, a widely used excitation–contraction uncoupling agent, decreases calcium (Ca2+) buffer affinity (increased buffer dissociation constant), leading to elevated diastolic Ca2+ levels, increased sarcoplasmic reticulum Ca2+
Izzatullo Sobitov   +8 more
wiley   +1 more source

Laser-assisted fabrication of gold nanoparticle-composed structures embedded in borosilicate glass. [PDF]

open access: yesBeilstein J Nanotechnol, 2017
Nedyalkov N   +7 more
europepmc   +1 more source

Mathematical model of the zebrafish ventricular cardiomyocyte action potential and calcium transient

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This study presents the development and validation of the first biophysically detailed computational model of the zebrafish ventricular action potential (AP). The model is based on a human cardiomyocyte framework and reparameterized using published and newly generated patch‐clamp recordings of zebrafish ionic currents.
Ludovica Cestariolo   +5 more
wiley   +1 more source

Transport‐related effects on intrinsic and synaptic properties of human cortical neurons: A comparative study

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend In this study, we investigated how transporting brain slices influences the electrophysiological and morphological properties of human cortical neurons. Whole‐cell patch‐clamp recordings were obtained from acute slices prepared from tissue collected during epilepsy or tumor surgeries, either on‐site or off‐site, after ...
Guanxiao Qi   +7 more
wiley   +1 more source

Mutations in ammonia transporter RhBG that impair NH3/NH4+ transport in patients with chronic kidney disease

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Overview of the study design and workflow. Left: screening for RhBG mutations associated with chronic kidney disease. Right: functional validation of identified mutations using Xenopus oocyte electrophysiology with two‐electrode voltage clamp technique and intracellular pH measurements, showing impairment of NH3/NH4+ transport ...
He Zhou   +3 more
wiley   +1 more source

Magnetic Glass Ceramics by Sintering of Borosilicate Glass and Inorganic Waste. [PDF]

open access: yesMaterials (Basel), 2014
Ponsot IMMM   +6 more
europepmc   +1 more source

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