Results 61 to 70 of about 59,701 (228)

In vitro and in vivo evaluation of cephalosporins for the treatment of Lyme disease. [PDF]

, 2018
BackgroundLyme disease accounts for >90% of all vector-borne disease cases in the United States and affect ~300,000 persons annually in North America.
Ambati, Aditya, Babar, Mustafeez Mujtaba, Inayathullah, Mohammed, Kim, Kwang-Min, Maguire, Peter, Parekh, Mansi B, Pothineni, Venkata Raveendra, Potula, Hari-Hara Sk, Rajadas, Jayakumar, Tayebi, Lobat   +9 more
core  

m.10010T>C Mitochondrial Disease: A Case Report With Hypoparathyroidism and Review of the Literature

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Mitochondria are essential intracellular organelles that play a critical role in cellular metabolism, including the regulation of intracellular calcium signaling. Advances in genomic sequencing have facilitated the identification of rare pathogenic mitochondrial DNA (mtDNA) genetic variants in patients with unexplained endocrine disorders.
Jacob Mohr, Anja Lisbeth Frederiksen, Morten Duno, Anne Pernille Hermann, Trine Maxel Juul, Simone Rask Nielsen   +5 more
wiley   +1 more source

Prevalence of Borrelia burgdorferi sensu lato genetic markers in blood-sucking ticks in suburban park zones in Saint Petersburg

Инфекция и иммунитет, 2020
Tick-borne bacterial and viral infections are widespread in middle latitudes of the Northern hemisphere. Natural foci of such infections coincide with geographic areas inhabited by ixodid ticks.
Yu. A. Panferova, A. N. Vaganova, O. A. Freylikhman, K. A. Tretyakov, S. G. Medvedev, A. O. Shapar’, N. K. Tokarevich   +6 more
doaj   +1 more source

Vaccines for Lyme Borreliosis: Facts and Challenges

Folia Veterinaria, 2022
Lyme borreliosis (LB) is a multisystem infectious disease abundant in the northern countries of the world and is caused by Borrelia species. Vaccination against LB is an effective way to prevent and reduce the number of diseases in endemic areas. Several
Bodnárová S., Čížková D., Hudáková N., Mangesh Bhide M.   +3 more
doaj   +1 more source

Psychiatric manifestations of multiple sclerosis and acute disseminated encephalomyelitis [PDF]

, 2006
It is unusual for acute disseminated encephalomyelitis and multiple sclerosis to present as purely psychiatric disorders. We report five patients with such demyelinating diseases and symptoms of psychosis, depression or anxiety.
Brinar, Marko, Brinar, Vesna V., Habek, Mario, Poser, Charles M.   +3 more
core   +1 more source

Host, vector, and parasite dynamics: exploring intrinsic and extrinsic factors shaping tick‐borne filarial nematode transmission

Biological Reviews, EarlyView.
ABSTRACT Tick‐borne filarial nematodes are a complex and understudied group of parasites that rely on ticks for transmission in vertebrates. This review examines how intrinsic and extrinsic factors may influence the successful transmission of filarial nematodes in tick vectors, drawing insights from extensively studied haematophagous dipteran vector ...
Oluwaseun D. Ajileye, Gabriel L. Hamer, Sarah A. Hamer, Guilherme G. Verocai, Jessica E. Light   +4 more
wiley   +1 more source

Ornithodoros kalahariensis, a potential vector for Candidatus Borrelia kalaharica

Ticks and Tick-Borne Diseases
Candidatus Borrelia kalaharica was proposed as bacterial species in 2016 using DNA extracted from a traveller returning from Southern Africa. We investigated DNA of three soft ticks collected in the Kalahari Game Reserve near Maun, Botswana via PCR.
Volker Fingerle, Heidelore Hofmann, Christine Hartberger, Gabriele Margos   +3 more
doaj   +1 more source

Modeling the effects of variable feeding patterns of larval ticks on the transmission of Borrelia lusitaniae and Borrelia afzelii [PDF]

, 2017
Spirochetes belonging to the Borrelia burgdoferi sensu lato (sl) group cause Lyme Borreliosis (LB), which is the most commonly reported vector-borne zoonosis in Europe. B. burgdorferi sl is maintained in nature in a complex cycle involving Ixodes ricinus
Bertolotti, Luigi, Ferreri, Luca, Giacobini, Mario, Mannelli, Alessandro, Perazzo, Silvia, Venturino, Ezio   +5 more
core   +2 more sources

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

iNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu, Gayani K. Nanayakkara, Yifan Lu, Fatma Saaoud, Keman Xu, Ying Shao, Bo Yuan, Shih‐Yu Hung, Haiyan Xiang, Xianwei Wang, Sadia Mohsin, Sheng Wu, Xiaolei Liu, Juncheng Wei, Zhengjie Zhou, Beata Kosmider, Mingui Fu, Laisel Martinez, Roberto Vazquez‐Padron, Wenhui Hu, Shuping Ge, Hong Wang, Xiaofeng Yang   +22 more
wiley   +1 more source

Could the Optiplex Borrelia assay replace the traditional, two-step method of diagnosing Lyme disease?

Annals of Agricultural and Environmental Medicine, 2022
Introduction and objective Serological assays for Lyme disease (LD) routinely performed in laboratories often give inconclusive results, thereby making correct diagnosis difficult and delaying treatment.
Iwona Wojciechowska-Koszko, Justyna Dziatlik, Paweł Kwiatkowski, Paulina Roszkowska, Monika Sienkiewicz, Barbara Dołęgowska   +5 more
doaj   +1 more source