Results 201 to 210 of about 50,331 (233)
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Borrelia burgdorferi and localized scleroderma
Clinics in Dermatology, 1994L yme borreliosis is a multisystemic disorder caused by the spirochete Borrelia burgdorferi and transmitted by the Ixodes tick. The initial manifestations of the disease are the characteristic skin lesion, erythema migrans, and symptoms of general malaise (stage I).
TREVISAN, GIUSTO +2 more
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Microbiology of Borrelia burgdorferi
Seminars in Neurology, 1997This article reviews the natural history, taxonomy, physical structure, growth requirements, and molecular structure of Borrelia burgdorferi sensu lato, the causative agent of Lyme disease. These spirochetal bacteria are maintained in nature through an infectious cycle between wild mammals and ticks.
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Transformation of Borrelia burgdorferi
Current Protocols, 2021AbstractTransformation techniques used to genetically manipulate Borrelia burgdorferi, the agent of Lyme disease, play a critical role in generating mutants that facilitate analyses of the role of genes in the pathophysiology of this bacterium.
J, Seshu +2 more
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Detection of glycoproteins in Borrelia burgdorferi
Archives of Microbiology, 1992The presence of carbohydrates on proteins of Borrelia burgdorferi, the causative agent of Lyme disease, was investigated by using a digoxigenin labeling method together with Schiff staining and N-glycosidase F assay. The two major outer surface exposed proteins of 31 kDa and 34 kDa showed to be glycosylated and gel filtration high pressure liquid ...
V, Sambri, C, Stefanelli, R, Cevenini
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Asymptomatic Borrelia burgdorferi infection
Medical Hypotheses, 2001Little is known about the natural history of asymptomatic Borrelia burgdorferi infection. Our analysis of the asymptomatic infections diagnosed serologically in a recent OspA vaccine trial conducted in the United States (N Engl J Med 1998;339: 209-215), suggests that the natural history of this event is more benign than that reported for untreated ...
G P, Wormser +3 more
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The recA gene of Borrelia burgdorferi
Gene, 1995The nucleotide sequence of the Borrelia burgdorferi (Bb) Sh-2-82 recA gene has been determined using PCR-based approaches without the construction of a genomic library. The gene should encode a protein of 365 amino acids which is highly homologous to other known RecA proteins.
K, Dew-Jager, W Q, Yu, W M, Huang
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Seroprevalence of Borrelia burgdorferi in Romania
European Journal of Epidemiology, 2001In order to assess the seroprevalence of Borrelia burgdorferi in Romania and to define associated risk factors, a cross-sectional, observational study was performed in 13 districts during 1999. Sera from healthy blood donors (1,598) and from forestry workers (1,048) were tested. A two-step testing strategy was used in which sera were tested for anti-B.
A, Hristea +3 more
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Nonprotein Antigens of Borrelia burgdorferi
Journal of Infectious Diseases, 1993Preparative thin-layer chromatograms of chloroform-methanol extracts of Borrelia burgdorferi (B31) sonicates showed four fractions (Rf values of 0.84, 0.81, 0.66 and 0.61) that stained with iodine vapors, orcinol, or phospray, suggesting the presence of lipid-, carbohydrate-, and phosphorus-containing compounds.
C M, Wheeler +5 more
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Borrelia burgdorferi–Traveling incognito?
Microbes and Infection, 2006We outline in this review how Borrelia burgdorferi, the causative agent of Lyme disease, moves from the tick to the vertebrate host, and what molecules are potentially involved in this challenging commute. The survival strategies utilized by the spirochete during transmission and the initial stages of infection are discussed.
Erol, Fikrig, Sukanya, Narasimhan
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Linear chromosome of Borrelia burgdorferi
Research in Microbiology, 1989The DNA organization of several European and American isolates of Borrelia burgdorferi, the aetiological agent of Lyme disease, was analysed in pulse-field agarose gel electrophoresis. The results of in situ cell lysis in agarose plugs demonstrated a unique arrangement for the DNA of this spirochete.
C, Baril +3 more
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