Results 81 to 90 of about 5,451 (202)

Navigating infection by pathogenic spirochetes: The host‐bacteria interface at the atomic level

Protein Science, Volume 34, Issue 7, July 2025.
Abstract Pathogenic spirochetes bind and interact with various host structures and molecules throughout the course of infection. By utilizing their outer surface molecules, spirochetes can effectively modulate their dissemination, interact with immune system regulators, and select specific destination niches within the host.
Libor Hejduk, Norbert Müller, Adriana Rathner, Ján Štěrba, Shang‐Cheng Hung, Chia‐Lin Chyan, Ryan O. M. Rego, Martin Strnad   +7 more
wiley   +1 more source

Clinical Characteristics in Danish Children and Adults Diagnosed With Neuroborreliosis: A Retrospective Study From January 2016 to January 2024

European Journal of Neurology, Volume 32, Issue 7, July 2025.
ABSTRACT Introduction Lyme neuroborreliosis (NB), is caused by tick‐borne spirochetes in the Borrelia burgdorferi sensu lato (Bbsl) genospecies complex. Although the clinical manifestations of NB in adults and children are well documented, understanding neurobiological differences between these groups can improve diagnostic accuracy and treatment ...
Al‐Hasan Hussein Dos, Nina Vindegaard Sørensen, Malini Vendela Sagar, Anne‐Mette Lebech, Anders Hougaard, Christian Stenør   +5 more
wiley   +1 more source

Infection of Ixodes ricinus (Acari: Ixodidae) by Borrelia burgdorferi sensu lato in North Africa [PDF]

, 2017
Free-living adult Ixodes ricinus L. were collected in Amdoun, situated in the Kroumiry mountains in northwestern Tunisia (North Africa). Using direct fluorescence antibody assay, the infection rate of field-collected I.
Aeschliman, Andre, Bouattour, Ali, Gern, Lise, Gharbi, Mohamed, Ginsberg, Howard S., Hu, Chang Min, Zhioua, Elyes   +6 more
core  

The Borrelia afzelii outer membrane protein BAPKO_0422 binds human Factor-H and is predicted to form a membrane-spanning beta-barrel [PDF]

, 2015
The deep evolutionary history of the Spirochetes places their branch point early in the evolution of the diderms, before the divergence of the present day Proteobacteria.
Adam Dyer, Albrecht, Bagos, Barcena-Uribarri, Behera, Bhide, Bordier, Brooks, Bunikis, Cabello, Casjens, Coutte, Crago, Crother, Cullen, Di, Dietrich, Eddy, Eswar, Fairman, Feng, Finn, Fraser, Freeman, Gemma Brown, Gessmann, Greene, Guina, Heffernan, Hong, Jaroszewski, Kenedy, Koebnik, Kopp, Kraiczy, Kurtenbach, Lenhart, Lenka Stejskal, Livengood, Margos, Mertins, Mittal, Nair, Oksi, Ornstein, Ostberg, Paetzel, Pautsch, Petersen, Peter R. Laity, Pettersen, Prasadarao, Preac-Mursic, Pugsley, Pulzova, Richard J. Bingham, Robert, Rogovskyy, Schmidli, Schulz, Setubal, Skare, Sperisen, Steere, Struyve, Sugawara, Svergun, Tamm, Thein, Tilly, Tommassen, Vogt, Volkov, Xie, Yamashita, Yang, Zhang   +76 more
core   +1 more source

Heterologous Surface Display Reveals Conserved Complement Inhibition and Functional Diversification of Borrelia burgdorferi Elp Proteins

Molecular Microbiology, Volume 124, Issue 1, Page 77-90, July 2025.
A novel approach using the Pseudomonas syringae ice nucleation protein (INP) system to present Borrelia burgdorferi lipoproteins on the surface of Escherichia coli reveals conservation of complement inhibitory functions among uncharacterized OspE/F‐like leader peptide (Elp) proteins.
Nathan Hill, Lara M. Matulina, Cameron MacIntyre, M. Amine Hassani, Sheila Thomas, Matteo Luban, Isabelle Ward, Amina Abdalla, John M. Leong, Brandon L. Garcia, Jacob E. Lemieux   +10 more
wiley   +1 more source

The Propensity of Different Borrelia burgdorferi sensu stricto Genotypes to Cause Disseminated Infections in Humans [PDF]

The American Journal of Tropical Medicine and Hygiene, 2008
Lineages of Borrelia burgdorferi, the bacterium that causes Lyme disease, can be characterized by distinct alleles at the outer surface protein C (ospC) locus. The lineages marked by ospC genotypes have been shown to be differentially invasive in different species of mammals, including humans; genotypes A, B, I, and K effectively disseminate to human ...
Daniel E, Dykhuizen, Dustin, Brisson, Sabina, Sandigursky, Gary P, Wormser, John, Nowakowski, Robert B, Nadelman, Ira, Schwartz   +6 more
openaire   +2 more sources

Functional vertebrate group diversity differentially impacts vector‐borne pathogen transmission and genetic diversity

Ecosphere, Volume 16, Issue 6, June 2025.
Abstract Anthropogenic land use change has led to considerable biodiversity loss, affecting ecosystem functions with unresolved consequences for zoonotic disease transmission. Functional diversity is understudied but potentially important for understanding the role of biodiversity because many zoonotic disease systems are maintained by species with ...
Marie Lilly, Arielle Crews, Alexandra Lawrence, Jordan Salomon, Samantha Sambado, Liliana Cerna, Kacie Ring, Ceili Peng, Grace Shaw, Shannon Summers, Andrea Swei   +10 more
wiley   +1 more source

The Release of Non‐Native Gamebirds Is Associated With Amplified Zoonotic Disease Risk

Ecology Letters, Volume 28, Issue 4, April 2025.
Spillback is potentially an important mechanism by which non‐natives contribute to zoonotic disease emergence. We capitalise on quasi‐experimental releases of non‐native pheasants (Phasianus colchicus) to compare native pathogen prevalence between sites with similar local conditions but different non‐native densities. Prevalence of Borrelia sp.
Emile Michels, Kayleigh Hansford, Sarah E. Perkins, Robbie A. McDonald, Jolyon M. Medlock, Barbara Tschirren   +5 more
wiley   +1 more source

Preferential Protection ofBorrelia burgdorferiSensu Stricto by a Salp15 Homologue inIxodes ricinusSaliva [PDF]

The Journal of Infectious Diseases, 2008
Ixodes ticks are the main vectors for Borrelia burgdorferi sensu lato. In the United States, B. burgdorferi is the sole causative agent of Lyme borreliosis and is transmitted by Ixodes scapularis. In Europe, 3 Borrelia species-B. burgdorferi, B. garinii, and B. afzelii-are prevalent, which are transmitted by Ixodes ricinus. The I.
Hovius, J. W., Schuijt, T. J., de Groot, K. A., Roelofs, J. J. T. H., Oei, G. A., Marquart, J. A., de Beer, R., van 't Veer, C., van der Poll, T., Ramamoorthi, N., Fikrig, E., van Dam, A. P.   +11 more
openaire   +2 more sources

Identification of tick-borne pathogens in ticks feeding on humans in Turkey.

PLoS Neglected Tropical Diseases, 2014
BackgroundThe importance of tick-borne diseases is increasing all over the world, including Turkey. The tick-borne disease outbreaks reported in recent years and the abundance of tick species and the existence of suitable habitats increase the importance
Ömer Orkun, Zafer Karaer, Ayşe Çakmak, Serpil Nalbantoğlu   +3 more
doaj   +1 more source