Results 111 to 120 of about 7,111,790 (225)

The PART randomised trial protocol: Partial Ablation versus Radical Treatment for prostate cancer

BJU International, EarlyView.
Objectives Primary objective: to determine whether prostate gland partial ablation (PA) has non‐inferior oncological treatment success vs radical treatment (RT) of localised intermediate‐risk prostate cancer (irPCa). Secondary objectives: to compare (i) participant‐reported urinary and sexual dysfunction side effects, (ii) short/medium term serious ...
Richard J. Bryant, Tom Leslie, Marc Laniado, Abhishek Sharma, Alistair Grey, John Withington, Christopher Blick, Edward Streeter, Sanjeev Kotwal, Oliver Hulson, William Cross, Daniel W. Good, Altan Omer, Taimur T. Shah, Nishant Bedi, Luke Stroman, Caroline Moore, Prasanna Sooriakumaran, Hashim U. Ahmed, Simon F. Brewster, Vicki S. Barber, Aimi Hewitt, Clare Calvert, Jessica Scaife, Derek Shepherd, Filipa Landeiro, Jane Wolstenholme, Philip Camilleri, Clare Verrill, Shelagh Lovell, Martin Pirkl, Fergus Gleeson, Roxanne Williams, Jo Cook, Catherine R. Holt, Martyn Hill, Jonathan Cook, James Radford, Ioana R. Marian, Ruth Macpherson, Daisy Elliott, Jenny L. Donovan, Freddie C. Hamdy   +42 more
wiley   +1 more source

New biosensors and transgenic mice for multiplex cGMP imaging

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a versatile second messenger that is important for human (patho‐)physiology and pharmacotherapy. Live‐cell imaging of cGMP with biosensors allows to elucidate its spatiotemporal dynamics in real time under close‐to‐native conditions. However, to monitor two separate cGMP pools or cGMP/cAMP
Markus Wolters, Martin Thunemann, Barbara Birk, Susanne Feil, Viacheslav O. Nikolaev, Moritz Lehners, Robert Feil   +6 more
wiley   +1 more source

Boston University Symphony Orchestra, March 4, 2004 [PDF]

, 2004
This is the concert program of the Boston University Symphony Ochestra performance on Thursday, March 4, 2004 at 8:00 p.m., at the Tsai Performance Center, 685 Commonwealth Avenue, Boston, Massachusetts.
School of Music, Boston University
core   +1 more source

Adding Intratumoral Antibody‐Photoabsorber Conjugate Improves Efficacy of Near‐Infrared Photoimmunotherapy (NIR‐PIT)

Cancer Science, EarlyView.
Intravenous (IV) or intratumoral (IT) cetuximab distribution in A431 tumor (essence of Figure 2). ABSTRACT Near‐infrared photoimmunotherapy (NIR‐PIT) is a new type of cancer treatment that specifically kills target cells while sparing normal tissue. This treatment induces cancer cell death by activating a photoreactive dye with near‐infrared light in ...
Miyu Kano, Aki Furusawa, Seiichiro Takao, Makoto Kano, Motofumi Suzuki, Hiroshi Yamamoto, Shuhei Okuyama, Ko Kitamura, Peter L. Choyke, Hisataka Kobayashi   +9 more
wiley   +1 more source

Circadian rhythms of metabolite abundance in Drosophila are largely driven by time of feeding

The FEBS Journal, EarlyView.
Circadian clocks exist in the brain and peripheral tissues such as the Drosophila fat body. Single‐nuclei transcriptomics reveal that the fat body clock generates time‐of‐day differences in metabolic gene transcription, which may also be indirectly controlled by brain clocks.
Sumit Saurabh, Charlene Y. P. Guerrero, Madelyn R. Cusick, Amanda J. Samaras, Taylor M. Stephenson, Sebastian L. Kirkpatrick, Gregory J. Matthews, Daniel J. Cavanaugh   +7 more
wiley   +1 more source

Neurokinin‐1 receptor antagonist (maropitant) for treatment of chronic idiopathic rhinitis in dogs: a pilot study

Journal of Small Animal Practice, EarlyView.
Objectives Chronic idiopathic rhinitis is a common canine nasal disease with unknown aetiology and poor response to treatment. Neurokinin‐1 receptor activation has been associated with rhinitis in experimental animals. The aim of this pilot study was to compare the effects of oral neurokinin‐1 receptor antagonist (maropitant) with placebo on clinical ...
H. Neittaanmäki, M. Rajamäki, N. Airas, A. Tilamaa, S. Viitanen   +4 more
wiley   +1 more source

Incidence and predicting factors of inadequate bowel preparation for colonoscopy: A cross‐sectional study

JGH Open
Background and Aim Adequate bowel preparation is necessary for optimal colonoscopy. Inadequate bowel preparation results in increased costs and imprecise colonoscopy results. This study aims to determine the incidence and risk factors of inadequate bowel
Alireza Asgari, Fateme Ziamanesh, Ali Aliasgari, Amir Ali Sohrabpour   +3 more
doaj   +1 more source

Diet and Care Mediate the Effects of Parenting and Nutrition Interventions on Childhood Infections

Maternal &Child Nutrition, EarlyView.
ABSTRACT The effect of community‐based multi‐input interventions that promote health, nutrition, and development on childhood infections, and the pathways that explain these effects remain unclear. We conducted a secondary analysis of a factorial‐designed clustered randomized controlled trial (N = 1489) conducted in rural Pakistan to estimate the ...
Nazia Binte Ali, Arjumand Rizvi, Saima Siyal, Wafaie W. Fawzi, Aisha K. Yousafzai, Christopher R. Sudfeld   +5 more
wiley   +1 more source

Comparison of the efficacy and tolerability of elobixibat plus sodium picosulfate with magnesium citrate and split-dose 2-L polyethylene glycol with ascorbic acid for bowel preparation before outpatient colonoscopy: a study protocol for the multicentre, randomised, controlled E-PLUS trial

BMC Gastroenterology
Background Sodium picosulfate (SP)/magnesium citrate (MC) and polyethylene glycol (PEG) plus ascorbic acid are recommended by Western guidelines as laxative solutions for bowel preparation.
Kinichi Hotta, Yosuke Otake, Daisuke Yamaguchi, Yuichi Shimodate, Norihiro Hanabata, Hiroaki Ikematsu, Yohei Yabuuchi, Yasushi Sano, Ryo Shimoda, Shinya Sugimoto, Mari Oba, Hiroyuki Takamaru, Kouichiro Kimura, Yoshihiro Kishida, Kazunori Takada, Sayo Ito, Kenichiro Imai, Kazuya Hosotani, Tatsuro Murano, Masayoshi Yamada, Kensuke Shinmura, Rio Takezawa, Michito Tomonaga, Yutaka Saito   +23 more
doaj   +1 more source

Boston University Symphony Orchestra and Women of the Boston University Symphonic Chorus with Boston University Theater Division, April 20, 1994 [PDF]

, 1994
This is the concert program of the Boston University Symphony Orchestra and Women of the Boston University Symphonic Chorus with Boston University Theater Division performance on Wednesday, April 20, 1994 at 8:00 p.m., at the Tsai Performance Center, 685
School of Music, Boston University
core