Results 131 to 140 of about 227,908 (260)
Generation of the Camptothecin Scaffold by a Flavin‐Catalyzed Photooxidative Skeletal Reorganization
The biosynthetic pathway of the anticancer drug precursor camptothecin involves an enigmatic skeletal reorganization from a 6/5/6 tetrahydro‐β‐carboline to a 6/6/5 pyrroloquinoline ring system. Here, we show that this transformation can be achieved by photooxidation with flavin cofactors, such as flavin mononucleotide (FMN) as catalysts.
Shenyu Liu +6 more
wiley +2 more sources
Vegetation of <i>Ranunculus lateriflorus</i> (Ranunculaceae) in the Latorica (Latorytsia) River catchment (Slovakia and Ukraine). [PDF]
Dudáš M +4 more
europepmc +1 more source
Abstract Premise Budding speciation occurs when peripheral populations adapt to local ecological conditions and “bud” off from a widespread progenitor species. Traditionally regarded as rare because of its sympatric and parapatric nature, budding speciation is largely understudied.
Eli J. Allen +3 more
wiley +1 more source
<i>Ceropegia gengmaensis</i> (Apocynaceae), a new species from Yunnan, China. [PDF]
Luo PR +7 more
europepmc +1 more source
Abstract Firefighters face an array of stressors due to the demands of their occupation, leading to a high prevalence of mental health challenges. Social prescribing represents a novel approach to healthcare that emphasizes a holistic view of health and wellbeing.
Janice Ikeda +2 more
wiley +1 more source
Retraction Note: Harnessing the application of halophytic flora biomass in the management of healthcare of local people in the Salt Range of Punjab. [PDF]
Nazish M +9 more
europepmc +1 more source
ABSTRACT Women with the FMR1 premutation (PM) are at increased risk for fragile X‐associated conditions (FXPAC), including cognitive and psychiatric features collectively termed fragile X‐associated neuropsychiatric disorders (FXAND). This study is the first to systematically investigate cognitive and psychiatric features in Italian female premutation ...
Federica Alice Maria Montanaro +5 more
wiley +1 more source
<i>Oreocharis sihuiensis</i> (Gesneriaceae), a critically endangered new species from Guangdong Province, China. [PDF]
Ji LB +5 more
europepmc +1 more source
ABSTRACT Major depression and suicide are critical public health concerns, particularly in underrepresented populations with unique genetic and sociocultural contexts. The Maya‐mestizo population presents the highest suicide rates in the country but remains understudied in psychiatric genetics. This study evaluated the association between three genetic
Marta Menjivar +3 more
wiley +1 more source

