Results 171 to 180 of about 583,682 (343)

Inhaling Eugenol Inhibits NAFLD by Activating the Hepatic Ectopic Olfactory Receptor Olfr544 and Modulating the Gut Microbiota

open access: yesAdvanced Science, EarlyView.
Inhalable eugenol (EUG) from clove oil attenuates NAFLD by activating hepatic olfactory receptor Olfr544, triggering cAMP/PKA/CREB signaling to enhance lipolysis/oxidation. EUG concurrently restores gut microbiota, enriching probiotics (L. reuteri XR23/L. johnsonii XR25) and metabolites (IPA/5‐HIAA) that suppress lipogenesis.
Xiao‐Ran Wang   +15 more
wiley   +1 more source

Dynamic Mosaicity Modulates Ion Transport in Stimuli‐Responsive Liquid Crystal Electrolytes

open access: yesAdvanced Science, EarlyView.
Thermotropic ionic liquid crystals provide a tunable platform for dimensionally‐controlled soft electrolytes, where anisotropy, nanoconfinement, and dynamic mosaicity govern ion transport behavior. In situ and operando analyses reveal a direct correlation between dynamic mosaicity and mesoscopic conductivity.
Hélène Pung   +11 more
wiley   +1 more source

Ultrathin, Unsinkable, Janus‐Faced Solar–Thermal Interfacial Evaporator for High‐Throughput Seawater Distillation and Solar‐Water Production

open access: yesAdvanced Science, EarlyView.
A nanostructured carbon‐coated porous polymeric scaffold is developed to accelerate the hydrological cycle, enabling solar–thermal freshwater production from saline water with reduced energy consumption and CO2 footprint. Abstract Solar–thermal distillation offers immense and hitherto untapped potential for energy‐efficient, sustainable freshwater ...
Mohammed Aslam Villan   +6 more
wiley   +1 more source

Root Meristem Maintenance Mechanisms are Key to Plant Defense Against Nanoplastics

open access: yesAdvanced Science, EarlyView.
Small nanoplastics can disrupt cell integrity and inhibit cell division in meristem zone of plant root. The plants can counteract the cell damage by upregulating genes associated with root meristem maintenance and increasing auxin accumulation by PIN2 transport inhibition.
Sirui Ma   +7 more
wiley   +1 more source

Structure‐Tailoring Cerium Nanozymes with Self‐Cascade ROS Scavenging Catalysis Modulate the Microbiota‐Gut‐Joint Axis for Rheumatoid Arthritis Therapy

open access: yesAdvanced Science, EarlyView.
A valence‐engineered CeOX nanozyme, with its Ce3+/Ce4+ ratio precisely controlled within the range of 0.27 to 0.93 through Au deposition, performs a self‐cascade oxidase‐superoxide dismutase‐peroxidase reaction, enabling continuous reactive oxygen species scavenging while minimizing oxygen generation.
Ge Wang   +10 more
wiley   +1 more source

An Inflammation‐Targeting Engineered Probiotic Escherichia coli Nissle 1917 with High Anti‐TNF‐α Nanobody Secretion Efficacy Alleviates Ulcerative Colitis

open access: yesAdvanced Science, EarlyView.
Ulcerative colitis therapy requires precise drug targeting. This study engineers a probiotic E. coli Nissle 1917 to surface‐display ANXA5, enabling specific binding to phosphatidylserine (PS) exposed on inflamed colonic epithelium for enhanced targeting and colonization.
Siqi Hua   +6 more
wiley   +1 more source

Botany

open access: yes, 1876
William Henry Brewer   +2 more
openaire   +3 more sources

Genome‐Wide Protein Interaction Analysis in Parasitic Gyrodactylus Flatworms–Fish Hosts System and Drug Target Identification

open access: yesAdvanced Science, EarlyView.
Genomic data offer a powerful tool for studying the molecular interactions between parasites and their hosts, but they remain scarce for parasitic monogenean flatworms. This study presents the first high‐quality phased genome assembly for monogeneans (Gyrodactylus kobayashii), and uses it to predict key interacting proteins between monogenean parasite ‐
Dong Zhang   +17 more
wiley   +1 more source

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