Results 71 to 80 of about 65,747 (262)
Nigericin‐Triggered Phosphodynamics in Inflammasome Formation and Pyroptosis
ABSTRACT Innate immune signaling relies heavily on phosphorylation cascades to mount effective immune responses. Although traditional innate immune signaling cascades following TLR4 stimulation have been investigated through a temporally quantitative phosphoproteomic lens, far fewer studies have applied these methods to distinct signaling following the
Vanya Bhushan+5 more
wiley +1 more source
Detecting and attributing climate change effects on vegetation: Australia as a test case
Climate change is contributing to vegetation changes that threaten life support systems. Yet, inherent climatic variability and past and present human actions—such as clearing, burning and grazing regimes—also alter vegetation and complicate understanding of vegetation change. Australian ecosystems exemplify such complexity.
Laura J. Williams+14 more
wiley +1 more source
ABSTRACT Protein crystallization remains a major bottleneck in X‐ray crystallography due to difficulties in achieving favorable molecular arrangements within the crystal lattice. While protein–protein interactions at molecular packing interfaces are crucial for determining crystallization conditions, methods for predicting crystal packing interfaces ...
Kuan‐Ju Liao, Yuh‐Ju Sun
wiley +1 more source
Synchronous Context-Free Grammars and Optimal Linear Parsing Strategies [PDF]
Synchronous Context-Free Grammars (SCFGs), also known as syntax-directed translation schemata, are unlike context-free grammars in that they do not have a binary normal form. In general, parsing with SCFGs takes space and time polynomial in the length of
Crescenzi, Pierluigi+4 more
core
Structural Variability of Pfam Domains Based on Alphafold2 Predictions
ABSTRACT Understanding the biological functions of proteins is one of the main goals of functional genomics. Such understanding will help control and manipulate biological processes to enhance desirable traits, including improved abiotic and biotic stress resistance in humans, animals, plants, and microbes.
Elly Poretsky+2 more
wiley +1 more source
Interleaving syntax and semantics in an efficient bottom-up parser [PDF]
John Dowding+3 more
openalex +3 more sources
CASP16 Protein Monomer Structure Prediction Assessment
ABSTRACT The assessment of monomer targets in the Critical Assessment of Structure Prediction Round 16 (CASP16) underscores that the problem of single‐domain protein fold prediction is nearly solved—no target folds were incorrectly predicted across all Evaluation Units.
Rongqing Yuan+6 more
wiley +1 more source
High biological activity of pyridazine carboxamides against a wide range of Ascomycetes led to identification of a new biochemical target for agrochemical fungicides – serine palmitoyl transferase. Abstract BACKGROUND Plant pathogens pose a significant threat to global agriculture and, thus to world food supplies, requiring the development of ...
Lionel Nicolas+13 more
wiley +1 more source
Mapping Thermal Conductivity at the Atomic Scale: A Step toward the Thermal Design of Materials
The site‐projected thermal conductivity method resolves the local thermal conduction contribution per atom by decomposing the Green–Kubo thermal conductivity tensor under the harmonic approximation. It highlights thermally active sites and “thermal defects” within disordered or amorphous materials, enabling spatially resolved insights into atomic‐scale
Chinonso Ugwumadu+3 more
wiley +1 more source
Visualization of the pipeline is divided into two primary segments: automated (i.e., the user adapts the code directly to build a custom computer vision model) and human‐in‐the‐loop (i.e., the user manually evaluates the output of the model). In step 1, raw imagery data are selected for training and testing datasets; ideally, these datasets are ...
Lindsay Veazey+3 more
wiley +1 more source