Targeting the Menin–KMT2A Axis in Acute Leukemia: From Epigenetic Dependency to Clinical Translation
ABSTRACT Acute leukemias characterized by a shared epigenetic dependency on the menin–KMT2A axis rely on aberrant HOX‐driven transcriptional programs that sustain leukemic self‐renewal and impair differentiation. This dependency is most evident in KMT2A‐rearranged and NPM1‐mutated acute myeloid leukemia (AML), but also extends to other HOX‐dependent ...
Antonella Bruzzese +12 more
wiley +1 more source
Impact of bottom ash addition on Pleurotus ostreatus cultivation on coffee ground substrate. [PDF]
Hnydiuk-Stefan A +8 more
europepmc +1 more source
Research on Pavement Performance of Cement-Stabilized Municipal Solid Waste Incineration Bottom Ash Base. [PDF]
Shi C, Li J, Sun S, Han H.
europepmc +1 more source
First attempt at using a synthetic diet in short‐lived killifish, a vertebrate model of ageing
Abstract Diet standardization of model organisms is crucial for experimental consistency and repeatability in laboratory research, yet laboratory fish often lack species‐specific, open‐formula standardized diets. This study aims to address this gap by testing the effect of macronutrient content on the performance of Nothobranchius furzeri, an ...
Jakub Žák, Milan Vrtílek
wiley +1 more source
Alkali-Activated Binder of Municipal Solid Waste Incineration Bottom Ash at Lower pH Levels. [PDF]
Tamošaitis G, Vaičiukynienė D.
europepmc +1 more source
Self-Compacting Recycled Concrete Using Biomass Bottom Ash. [PDF]
Cabrera M +4 more
europepmc +1 more source
Abstract Atlantic herring Clupea harengus are total spawners that exhibit a large degree of reproductive plasticity and have substantial intra‐annual variation in their energetic condition. Recent research suggests that the species may be declining in energetic condition in the northwest Atlantic Ocean from the few historical records, but comparisons ...
Joseph B. Warren +2 more
wiley +1 more source
Enhanced fruit preservation using compressed stabilized earth blocks and municipal solid waste incinerator bottom ash in pyramid structures. [PDF]
Poyyamozhi M +6 more
europepmc +1 more source
The Political Economy of Attention: Media Salience, Voter Cognition, and Electoral Accountability
ABSTRACT We review conceptual and empirical contributions to the political economy of attention, with a focus on how attention allocation shapes political behavior and electoral accountability. The review distinguishes between endogenous (goal‐directed) and exogenous (stimulus‐driven) attention and examines how these concepts are incorporated into ...
Patrick Balles +2 more
wiley +1 more source
A Geologic Si‐O‐C Pathway to Incorporate Carbon in Silicates
This book is Open Access. A digital copy can be downloaded for free from Wiley Online Library.
Explores the behavior of carbon in minerals, melts, and fluids under extreme conditions
Carbon trapped in diamonds and carbonate-bearing rocks in subduction zones are examples of the continuing exchange of substantial carbon ...
Alexandra Navrotsky +2 more
wiley +1 more source

