Results 91 to 100 of about 13,876,063 (349)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Journal of Marine Science and EngineeringAlong-slope bottom currents and down-slope (gravity-driven) turbidity currents coexist in the ocean and interact during their flow processes. The interaction between turbidity currents and bottom currents plays a crucial role in determining the lateral ...
Renqian Zhang +7 more
doaj +1 more source
$b \to s \gamma$ Decay and Right-handed Top-bottom Charged Current
, 1995 We introduce an anomalous top quark coupling (right-handed current) into Standard Model Lagrangian. Based on this, a more complete calculation of $b \to s\gamma $ decay including leading log QCD corrections from $m_{top}$ to $M_W$ in addition to ...
A.J. Buras +34 more
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Explicit Modeling of Solid Ocean Floor in Shallow Underwater Explosions
Shock and Vibration, 2013 Current practices for modeling the ocean floor in underwater explosion simulations call for application of an inviscid fluid with soil properties. A method for modeling the ocean floor as a Lagrangian solid, vice an Eulerian fluid, was developed in order
A.P. Walters, J.M. Didoszak, Y.W. Kwon
doaj +1 more source
General characteristics of current in front of Port Said, Egypt
Egyptian Journal of Aquatic Research, 2017 This paper is a preliminary investigation of the general characteristics of the current in front of the coastal Mediterranean city: Port Said, Egypt. The study of the current regime in front of Port Said helps environmental engineers to tackle problems ...
Mohamed S. Elsharkawy +2 more
doaj +1 more source
High Energy Benthic Boundary Layer Experiment (HEBBLE): Preliminary program plan and conceptual design [PDF]
Deep sea processes of flow-sediment interaction, particularly the role of high energy ocean bottom current events in forming the seafloor topography, transporting material, and mixing the bottom of the water column are examined.
Frewing, K.
core +1 more source
Comparison of habitat-based indices of abundance with fishery-independent biomass estimates from bottom trawl surveys [PDF]
, 2012 Rockfish species are notoriously difficult to sample with multispecies bottom trawl survey methods. Typically, biomass estimates have high coefficients of variation and can fluctuate outside the bounds of biological reality from year to year.
Martin , Michael H. +1 more
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The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
The impact of deep-sea fisheries and implementation of the UNGA Resolutions 61/105 and 64/72. Report of an international scientific workshop [PDF]
, 2011 The scientific workshop to review fisheries management, held in Lisbon in May 2011, brought together 22 scientists and fisheries experts from around the world to consider the United Nations General Assembly (UNGA) resolutions on high seas bottom ...
A. Benn +22 more
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