Results 71 to 80 of about 3,555,401 (304)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Current effects on scattering of surface gravity waves by bottom topography

open access: yes, 2005
Scattering of random surface gravity waves by small amplitude topography in the presence of a uniform current is investigated theoretically. This problem is relevant to ocean waves propagation on shallow continental shelves where tidal currents are often
Ardhuin, Fabrice, Magne, Rudy
core   +3 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Spatial Variability of the Hydrochemical Structure in Bottom Gravity Current in the Vema Fracture Zone

open access: yesRussian Journal of Earth Sciences
The Vema Fracture Zone is located in the North Atlantic Ridge and extends along 11°N from 38 to 46°W. It is the main pathway for the spreading of Antarctic Bottom Water to the Northeast Atlantic.
Zuev Oleg, Seliverstova Anna M.
doaj   +1 more source

Improved construction of concrete viaducts with movable scaffolding systems in Spain [PDF]

open access: yes, 2016
The current paper relates the state of the art of construction of viaducts with a movable scaffolding system (MSS). Two different procedures are introduced: the traditional sequence and the new sequence applied to some viaducts in Spain.
Diaz de Terán, Jose Ramon   +3 more
core   +2 more sources

Bottom homogeneous layers in the Florida Current

open access: yesGeophysical Research Letters, 1974
A total of 495 STD traces obtained from surface to bottom casts made in transects of the Florida Current east of Miami is examined for bottom homogeneous layers. Bottom layers are seen at all stations; however, at none of the examined stations was a bottom layer a permanent feature.
Georges L. Weatherly, Pearn P. Niiler
openaire   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Adjustment of the basin-scale circulation at 26° N to variations in Gulf Stream, deep western boundary current and Ekman transports as observed by the Rapid array [PDF]

open access: yesOcean Science, 2009
The Rapid instrument array across the Atlantic Ocean along 26° N provides unprecedented monitoring of the basin-scale circulation. A unique feature of the Rapid array is the combination of full-depth moorings with instruments measuring temperature ...
S. A. Cunningham   +3 more
doaj  

Bottom-trapped currents as statistical equilibrium states above topographic anomalies [PDF]

open access: yes, 2012
Oceanic geostrophic turbulence is mostly forced at the surface, yet strong bottom-trapped flows are commonly observed along topographic anomalies. Here we consider the case of a freely evolving, initially surface-intensified velocity field above a ...
A. Venaille, Gill, Maltrud
core   +3 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

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