Results 131 to 140 of about 11,850,269 (338)

Nanotransformation and current fluctuations in exciton condensate junctions

open access: yes, 2012
We analyze the nonlinear transport properties of a bilayer exciton condensate that is contacted by four metallic leads by calculating the full counting statistics of electron transport for arbitrary system parameters.
A. Komnik   +7 more
core   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

New perspectives on deep-water sandstones: Implications

open access: yesPetroleum Exploration and Development, 2013
The emerging new concepts of sandy mass-transport deposits (SMTD) and bottom-current reworked sands (BCRS) have made a big impact on conventional turbidite concepts.
G. Shanmugam
doaj   +1 more source

Dilution in a dense bottom jet in cross currents

open access: yesWater Science and Technology, 1998
A 3-dimensional numerical model describing the dilution in the near field around dense vertical jets in a cross flow is formulated and validated against laboratory experiments. The validation shows that the model reproduces the flow pattern well, though the dilution is underestimated by 20%.
Petersen, O., Larsen, Torben
openaire   +2 more sources

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Dynamics of large-amplitude geostrophic flows over bottom topography [PDF]

open access: yesNonlinear Processes in Geophysics, 1997
We examine the interaction of near-surface and near- bottom flows over bottom topography. A set of asymptotic equations for geostrophic currents in a three-layer fluid is derived.
E. S. Benilov, P. V. Sakov
doaj  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Gas plumes and near-seafloor bottom current speeds of the southernmost Okinawa Trough determined from echo sounders

open access: yesTerrestrial, Atmospheric and Oceanic Sciences, 2019
Using echo sounders to detect gas plumes in seawater is common, especially in the context of hydrothermal circulation areas or gas hydrate-bearing cold seeps.
Ching-Hui Tsai   +7 more
doaj   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

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