Results 91 to 100 of about 1,538,323 (350)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Design of sediment oxygen demand (SOD) 'in-situ' measuring chamber and its application in several rivers [PDF]

open access: yes, 2001
Sediment oxygen demand is defined as the rate of dissolved oxygen removal from the water column by the decomposition of organic materials in the bottom sediments.
Mohamed, Maketab, Yusop, Zulkifli
core  

Effects of population density on the sediment mixing induced by the gallery-diffusor Hediste (Nereis) diversicolor O.F. Müller, 1776 [PDF]

open access: yes, 2006
The aim of this work was to quantify the intensity of sediment mixing induced by the gallery-diffusor (functional bioturbation group) Hediste diversicolor as a function of density, using particles tracers (luminophores).
Duport, Eric   +3 more
core   +6 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Microbial Diversity in Sediments from the Bottom of the Challenger Deep, the Mariana Trench

open access: yesMicrobes and Environments, 2018
The Challenger Deep is the deepest ocean on Earth. The present study investigated microbial community structures and geochemical cycles associated with the trench bottom sediments of the Challenger Deep, the Mariana Trench.
T. Nunoura   +11 more
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

On Gammaridae Distribution in Caspian Sea Bottom Sediments 

open access: yes‬‭Majallah-i ̒Ilmī-i Shīlāt-i Īrān, 1993
On Gammaridae Distribution in Caspian Sea Bottom ...
A. Zahmatkesh
doaj  

Chemical and environmental assessment of the bottom sediments in the Irtysh River (Tyumen Region, Russian Federation)

open access: yesVestnik MGTU, 2019
The total concentration of Al, Co, Fe, Mn, Pb, Cu, Zn, Sr, As, Cr, Ni has been determined in the test portions of the bottom sediments (sand, loamy sand, sandy loam, silt and clay loam) in the lower reach of the Irtysh River. Atomic emission spectroscopy
Zemtsova E. S.   +2 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Stratigrafi Sedimen Perairan Selat Rupat Bagian Timur [PDF]

open access: yes, 2014
The stratigraphy of bottom sediments was investigated in eastern waters of RupatStrait, Riau Province in June 2013. The analysis of sediment were conducted by twomethods i.e : grain-size analysis and ignition loss methods.
', R. (Rifardi)   +1 more
core  

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