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The Pretherapeutic History of Botulinum Neurotoxin [PDF]
Unintended intoxication with botulinum toxin (botulism) occurs only rarely, but its high fatality rate makes it a great concern for those in the general public and in the medical community. In the United States an average of 110 cases of botulism are reported each year.
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Complications of Botulinum Neurotoxin
Disease-a-Month, 2009Dave W. Lu, Jonathan Lippitz
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Future aspects of botulinum neurotoxins
Journal of Neural Transmission, 2007The future of botulinum neurotoxin (BoNT) development is expected to proceed along two lines: the development of novel indications and the development of novel products. New indications will likely be based on the neuromuscular mode of action of BoNTs, as well as action on primary sensory fibers and other neuronal types.
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Pharmacology of Botulinum Neurotoxins [PDF]
Bigalke, H., Naumann, Markus
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Tetanus and Botulinum Neurotoxins
1994Tetanus toxin and the botulinum toxins A, B, Cl, D, E, F, and G are proteins produced by bacilli of the genus Clostridium. The eight toxins have a similar structure, they are translocated into neurons by adsorptive endocytosis, and they act predominantly on nerve cells.
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