Results 141 to 150 of about 717,002 (287)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

National Water Policy

open access: yes
Concerns of the community needs to be taken into account for water resources development and management. The success of the National Water Policy will depend entirely on evolving and maintaining a national consensus and commitment to its underlying ...
Ministry of Water Resources GOI
core  

Water use in Pakistan's agricultural sector: water conservation under the changed climatic conditions

open access: yes, 2010
Pakistan’s economy heavily relies on agriculture sector which accounts for a quarter of its GDP and employs two-fifths of total labourforce. Pakistan is located in a semiarid to arid region where rainfall is very low.
Majeed, Zahid, Piracha, Awais (R13384)
core  

The effect of openings on combined bound water and water vapor diffusion in wood

open access: yes, 2008
This study was undertaken to estimate the effect of openings between cell walls on combined bound water and water vapor diffusion in wood. Using a newly developed model, the radial and tangential moisture diffusion coefficients can be predicted depending
Kang, Wook   +5 more
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Effect of grinding on the quantification of the bound water in tricalcium silicate

open access: yes, 2019
The effect of grinding of hydrated tricalcium silicate (C3S) pastes on the bound water content measured by TGA is investigated. The samples were subjected to different curing regimes at 20°C and 40°C at a constant water to cement ratio of 0.5.
Cizer, Ozlem, Joseph, Shiju
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Bound - ACE408.2

open access: yes
Cloth waving in the wind. Heartbeat sound. Slow motion of Chinese woman practising t’ai chi. Face superimposed. Hands, body and legs wrapped by cloth superimposed. Feet stepping out of cloth. Woman on sand and rocks at sea’s edge. VO: "Through the

core  

Phosphorus nutrition and tolerance of cotton to water stress: II. Water relations, free and bound water and leaf expansion rate

open access: yes, 2006
In previous experiments, increased leaf-Phosphorus (P) content with increasing P supply enhanced the individual leaf expansion and water content of fresh cotton leaves in a severely drying soil.
Pallaghy, Charles K.   +5 more
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

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